The present invention relates to novel alternative forms of human acetylcholinesterase (AChE) and nucleotide sequences encoding the same. The genes encoding the novel forms of human AChE have been identified in various malignant tumor cells. In a further aspect, the invention relates to a transgenic animal assay system for evaluating efficacy of drugs against cholinergic proteins, prior to or in t...

This invention pertains to integration of nonlinear parametric waveguide spectrometer (13) with a polyimide waveguide focusing mirror. The waveguide spectrometer uses nonlinear counter-propagating chi <2> interaction to simulate the action of a grating and produce the required chromatic dispersion. To map the near-field to far-field and separate different wavelength components, an organic-dielectr...

An object of the present invention is to provide a tread centering device which automatically detects the position of tread center and holds it in a straight form even when the center of tread is not positioned in a straight form. The device mainly comprises a plurality of detectors (28) for detecting a groove (27) for centering the tread (25), a holding plate (11) which is inserted into the detec...

The connector for fluid circuits, particularly the coolant circuit of an internal combustion engine (10), comprises a hose (16) of elastomeric material and at least one clamping clip (24), shaped as a ring (26) which can be opened along a generatrix and having means (28, 30) for varying the diameter of the ring (26). In its external surface adjacent at least one end, the hose (16) has a circumfere...

A device for producing focused acoustic pressure waves for therapeutic purposes, in particular for destroying concrements, calculi etc., includes a sound generating unit (1') generating pressure waves in a coupling medium (8); said waves are focused by a reflector (3). Said device can also include a locating device (11) for the concrements, calculi etc. to be destroyed. Said device is characterize...

A tape is closed in a ring shape and is made of a textile material, at least in part, of thermoplastically meltable fibres. The tape consists of a section (3) of a material web (2) and its ends are welded together in a butt joint.

The changeover switch (1) has not less than two input light guides (2) from which light can be injected into the switch. The light from the individual input guides can be injected into output light guides (3) by the switch in sequence or alternately. The switch consists of a partially opaque device (4) coupled to a corresponding output light guide which is connected to an analyser (8). The switch...

An assembly which separates floating solids from liquids incorporates a helical conveyer in its upper section. The novelty is that the helical screw conveyer (13) is positioned in an inclined attitude within the floatation chamber (10). Pref. the helical conveyer consists of two sections of different pitch linked by a universal joint (14). The passages in the upper conveyer section (13/1) incorpo...

The simultaneous effects of the electrical shock discharge and the ultrasound causes the material to be disintegrated, homogenised or separated. The fluid bath is a water bath (6). The equipment used comprises a container (1) which accommodates the fluid and the inserted material (5). An ultrasound producer (8) radiates into the fluid and a high voltage generator has at least one pair of electrode...

A combined vehicle battery and control unit has two batteries and a switch (r1) that is normally open for separate battery outputs, but is closed for charging up the batteries in parallel from the generator. One battery is used just by the starter motor, the other for electrical auxiliaries. They have different construction and different charge/discharge characteristics. The switch is controlled ...

As a sealing structure for a syringe, a water-proofing film is adhered to the surface of a cap (6), a barrel (3) and a cylinder body (2) to cover fitting areas therebetween. The film is made of synthetic resin having a melting point higher than the temperature of flowing water vapor in post sterilization. As a sliding valve for a syringe, an inclined lip (24) is continuously protruded from the out...

An automated highway system reduces the data processing requirements on the vehicles and distributes the processing requirements throughout the automated highway system infra-structure. In this system, a vehicle is detected by use of a vehicle on-board transponder. This transponder responds to an omni-directional radio frequency transmission from a highway control facility used by the automated hi...

PCT No. PCT/FR95/00338 Sec. 371 Date Sep. 24, 1996 Sec. 102(e) Date Sep. 24, 1996 PCT Filed Mar. 20, 1995 PCT Pub. No. WO95/25567 PCT Pub. Date Sep. 28, 1995A toe piece for a ski safety binding includes a jaw having two lateral arms. The lateral arms pivot about a pin. The return and holding forces during the elastic travel are proportional to the triggering threshold. The useful elastic travel is...

PCT No. PCT/DE95/00339 Sec. 371 Date Oct. 8, 1996 Sec. 102(e) Date Oct. 8, 1996 PCT Filed Mar. 10, 1995 PCT Pub. No. WO95/25275 PCT Pub. Date Sep. 21, 1995A miniaturized circulatory measuring chamber with integrated chemo- and/or biosensor elements including a substrate formed from a plate-shaped carrier. Within the plate-shaped carrier is inserted at least one containment tapering from a frontal ...

Precured tread (10) is moulded to an unvulcanised tyre casing (100) by placing both inside a smooth mould, inserting an inflatable bladder (80) inside the casing before closing the mould, inflating the bladder to expand the casing firmly into contact with the tread and to expand the tread so that it engages the smooth mould and forms an air-tight seal at an annular projection (60) radially above t...

A polyester composition used for thermoshrinkable films, wherein the composition comprises acid components including terephthalic acid and glycol components including ethylene glycol, and wherein the composition has a transformation ratio of 0.175 or more, is described.

Methods and apparatus for inspecting surface features of a substrate. In each configuration, at least one TDI sensor is used to image the portions of interest of the substrate, with those portions illuminated either with substantially uniform illumination or critical illumination. In one configuration, a substrate, is compared to the expected characteristic features prestored in a memory. In a sec...

By deriving the image formed by light specularly-reflected from substntially all of the convex (mirror-like) spherical surface of a bearing ball under test that is being illuminated with diffuse light, any defect in the bearing ball under test reveals itself as a light-contrast pattern in the otherwise substantially uniform diffuse background of the image. The inspection system comprises illuminat...

A swivellable fitting assembly has a housing with a stem with a rotatable nipple on the stem. The rotatable nipple is sealed and spaced from the nipple to enable rotation of the nipple or housing with respect to one another.

A process for the production of rigid, very substantially open-celled foams containing urethane and/or isocyanurate groups by reacting polyisocyanates with compounds containing at least two isocyanate-reactive groups whose equivalent weight is from about 9 to 800 per reactive group, in the presence of catalysts, surfactants and optionally physical blowing agents, flameproofing agents and other kno...