Fluoro substituted cycloalkanoindole derivatives are antagonists of formula I are antagonists of prostaglandins, and as such are useful for the treatment of prostaglandin mediated diseases.

SE REFIERE A COMPUESTOS DERIVADOS DE 5-ALQUINIL-PIRIMIDINAS DE FORMULA (1) DONDE R1 Y R2 SON CADA UNO CICLOALQUILO(C3-C8), ARILO(C6-C10), HETEROARILO DE 5 A 12 MIEMBROS, ENTRE OTROS; R3 ES H, HALOGENO, -CF3, -CN, ALQUILO(C1-C6), ENTRE OTROS; R4 ES ALQUILO(C1-C3), CICLOALQUILO(C3-C8), -CN, -NO2, ENTRE OTROS. SON COMPUESTOS PREFERIDOS LOS DE FORMULA (A), (B), ENTRE OTROS. SE REFIERE TAMBIEN A UNA CO...

A device for an air handling system, where the cooling beam has a pressure chamber (2), from which the volume flow in the supply air L1 out to the room is regulated with a regulating strip (6) that is mounted on the surfaces (9) in the pressure chamber and where the air flow L1 in the mixing chamber (4) gives an optimal flow pattern of the recirculating air flow L2 from the room and where those ai...

A cleaning arrangement (15, 26) for cleaning the drain area (13, 14) of a valve (1) with a cleaning media, where the cleaning arrangement includes at least one cleaning device (15, 26), which is preferably arranged in a mix proof valve (1) comprising at least a valve body (2), one or more valve seats (4, 7), a first valve plug (5) with a first stem (6) and a second valve plug (8) with a second ste...

The invention concerns a supercharger that has two rotors engaging into each other and is provided with a disc clutch. The disc clutch has driving (9) and driven (12) clutches connected with a drive shaft (7) and with one of the rotors, respectively. Furthermore, there is an axially displaceable pressing body (15) as well as actuation device (13) for the same and a deactuation spring (17). Accordi...

The invention regards a wind turbine comprising a least one turbine blade attached to a hub 10. The turbine blade comprises an inner part 2, comprising a load carrying structure 6 with a longitudinal axis 21 and aerodynamically active surfaces 7, which wholly or partly enclose the structure, joined to an outer part 3 by means of a joint 19. The joint 19 comprises a ring shaped bearing 8 and a blad...

The invention relates to an admixture for a cementitious composition comprising microfibrillar cellulose and/or a derivative thereof. The invention also relates to a method of manufacturing said admixture and to the use of the microfibrillar cellulose and/or a derivative thereof in the concrete admixture. The invention further relates to a cementitious composition comprising said admixture and met...

The invention relates to a system and method for reducing impurities on the anode or cathode side of a fuel cell. The system comprises the anode or cathode of a fuel cell, a fuel or oxidizer feed line for feeding fuel or oxidizer to the anode or cathode respectively, and a circulation line connected to the fuel or oxidizer feed line for circulating part of the fuel or oxidizer through it. Accordin...

The invention relates to a sample processing apparatus comprising a holder for a microtiter plate comprising a plurality of microwells, optical measurement unit for measuring optical responses of samples dosed to the microwells, and a computing unit configured to analyze the optical responses in order to detect dosing failures in said plurality of microwells, and if a dosing failure has been detec...

A bali rebound device for bali games comprising: a frame structure, a sheet being detachably attached directly to the front of the frame structure and adjusting means connected to the frame structure, the adjusting means being able to move part of the frame structure, whereby the tension of the sheet can increase or decrease. By stretching the sheet, it is possible to increase the rebound force of...

A cleaning system for cleaning one or more valve seats in a valve and for cleaning one or more interior surfaces of said valve with a cleaning agent, where said cleaning Sys tem are preferably arranged in a mixproof valve consisting of at least a valve body, one or more valve seats, a first valve plug with a first stem and a second valve plug with a second stem, the second valve plug having a cent...

A level entry bore welder that is easier to use and less expensive to purchase. It has an adjustable step feature that allows the operator to control the bead placement inside the bore of a work piece. It includes a simple remote control apparatus that adjusts the welding torch rotation speed as a function of the diameter of the bore. The remote control apparatus also permits the operator to turn ...

The present invention relates to a modular canopy that comprises at least one cover sheet (12), at least a pair of bearing brackets (10) for said cover sheet (12), at least one eaves (8), one connection coupling (5) between said eaves (8) and bearing brackets (10), means (3) for stable connection of the eaves (8) to said coupling (5); said constructive parts being all provided with means for mutua...