According to the preferred embodiments of the present invention, an apparatus and method for retaining keys is disclosed. The present invention provides a tensioning mechanism within the body of the key-retaining apparatus for "pinching" the shaft of a key when the shaft is inserted into the body of the key-retaining apparatus. The tensioning mechanism may take the form of a spring-loaded mechanis...

Padding element for the dorsal side of a diver's bottle-supporting backpack. Said padding element comprises a padded cushion capable of being fitted against the back part of the said backpack and having at its lower edge a padded cushion part hinged to it and capable of being either folded upwards, in order to increase the total thickness, and hence the padding action of the said cushion over the ...

There is disclosed a circuit and method for demultiplexing in a receiver a digital data stream including at least two types of data, so as to retain only those parts of the digital data stream required by the receiver. In one particular application, such a receiver is used in a television system having a digital set-top-box receiver. A first control circuit extracts a packet identifier from an inp...

A process of forming powder metal components which minimizes decarburization and oxidation of the component prior to final forging. The process begins by molding powder metal material into a preform configuration. The preform is delubricated to extract lubricant found in the pores of the preform. Passing the preform through a shot peening operation closes a majority of the surface pores creating a...

The present invention relates to the use of inhibitors of the expressed proteins of TCF target genes whose expression is regulated by TCF/beta-catenin complexes for the preparation of a therapeutical composition for the treatment of cancers in which TCF/beta-catenin signaling is deregulated. Such inhibitors can be antibodies, small molecules, antisense RNA and dsRNA for use in RNAi. The invention ...

A method for manufacturing a coated sheet that may form a coated layer having a uniform film thickness by a coating liquid even when a substrate has a large area is provided. A method for manufacturing a coated sheet to form a coated layer by a process including a process (1) for coating a coating liquid including a resin material and a solvent on a substrate, and a drying process (2) for drying a...

Described herein are genes whose expression are up-regulated or down-regulated in ovarian cancer. Related methods and compositions that can be used for diagnosis and treatment of ovarian cancer are disclosed. Also described herein are methods that can be used to identify modulators of ovarian cancer.

There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the CTSZ and CD24 genes, which are amplified colon cancer and/or ovarian cancer and/or breast cancer genes. The CTSZ and CD24 genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or vacc...

Genetic sequences are identified with expression levels that are upregulated or downregulated in human endometrium during the window of implantation. The endometrial signature of genes during the window of implantation provides diagnostic screening tests for patients with infertility and endometrial disorders, and endometriosis; and for targeted drug discovery for treating implantation-based infer...

A method of determining whether a subject is suffering from or at risk for developing cancer. The method includes preparing a nucleic acid sample from a subject, and identifying a single nucleotide polymorphism in the SERPINB13 gene. The presence of a single nucleotide polymorphism indicates that the subject is suffering from or at risk for developing cancer. Also disclosed is a method of treating...

An apparatus (31, 32, 132) and method for determining the concentration of a medically significant component (for example, glucose) of a biological fluid (for example, blood) comprise providing a cell (31) for receiving a sample of the fluid (for example, blood). The cell (31) supports a chemistry which reacts with the medically significant component (for example, glucose), and first and second te...

An exotherm reducing additive including a tetrahalogenated ionic compound and an exotherm reducing additive composition for organic polymer compositions including an exotherm reducing-effective amount of the tetrahalogenated ionic compound, a solvent for the tetrahalogenated ionic compound, and a diluent compatible with the tetrahalogenated ionic compound, the solvent and the organic polymer compo...

Electroactive pores, devices including one or more electroactive pores are described, and methods of delivering therapeutic agents using one or more electroactive pores are described.

A system for efficient delivery of radio frequency (RF) energy to cardiac tissue with an ablation catheter used in catheter ablation, with new concepts regarding the interaction between RF energy and biological tissue. In addition, new insights into methods for coagulum reduction during RF ablation will be presented, and a quantitative model for ascertaining the propensity for coagulum formation d...

A train control system includes positioning systems at the end of the train and at the front of the train, allowing the conductor or engineer to unambiguously determine that no cars of the train have become detached. The positioning system at the end of the train is also used to verify that the entire train has cleared a block. This information can be relayed to a dispatcher, thereby eliminating t...

A method of controlling an Automatic Guided Vehicle (AGV) system includes setting moving paths of the AGVs by taking into account task performing costs of cases for orders of all tasks to be performed by the AGVs, and controlling the AGVs according to the set moving paths. The setting of the moving paths includes calculating the cases for the orders of all the tasks to be performed by the AGVs cal...

PROBLEM TO BE SOLVED: To provide a process for determining whether a patient having a disease treated through imatinib administration such as CML (Current Model Logic) is sensitive to imatinib, i.e. to predict whether the administration of the patient with the imatinib is effective for treating the disease.

SOLUTION: Expression levels of two or more genes selected from among 77 specific gen...

PROBLEM TO BE SOLVED: To provide a calcium-enriched food stable and having good texture which causes neither precipitation of a calcium salt in the manufacturing process of the calcium-enriched food nor formation of precipitation and flocculation by a reaction of calcium with a protein or the like based on a technology which allows to stably add calcium to a food.

SOLUTION: A calcium salt h...

PROBLEM TO BE SOLVED: To provide a cyclone dust collecting device for a vacuum cleaner by which a grill arranged at an exhaust port in a cyclone body is easily maintained.

SOLUTION: The device includes: the cyclone body having an intake port and the exhaust port so as to form a rotational gas flow concerning sucked air containing dust which flows-in through the intake port; a dust cup which...

PROBLEM TO BE SOLVED: To provide an application method and an application device for realizing simple and reliable sensing and control of the position of a valve element.

SOLUTION: The device for applying fluids to a moving substrate has at least one nozzle system 20 to which the fluid is supplied from a supply channel 40 coupled to a fluid source. A valve system 30 cooperated with the nozz...