Each heart valve prosthesis is supported and fixed by three identical pairs of brackets (3,4,5) staggered by 120 degrees from each other and joined by solid body links (7). The two curved brackets in opposite facing directions have lever arms of the same length. The first and second distal brackets are partly curved in the same direction and run parallel with each other so that gaps for inserting ...

In order to provide a nonmagnetic material for producing parts or coatings adapted for highly wear and corrosion intensive applications, said material comprising preformed particles made of tungsten carbide which are embedded in a metal phase made of a Ni-based alloy. It is suggested that the weight portion of said tungsten carbide particles is in the range between 30 wt.% and 65 wt.% and wherein ...

The present invention relates to a novel polypeptide chain forming a particular 3 dimensional fold characterized by a beta-sandwich. By altering the amino acid sequence in specific regions of the polypeptide of the invention novel binding characteristics are developed. Methods for the generation of a polypeptide according to the invention and uses of polypeptides of the invention are also describe...

To provide an ultrasonic sealing apparatus by which it is possible to prevent a sealing failure owing to the tunnel (through passage) seldom occurring in the step portions in the vicinity of the both end portions of the longitudinally sealed portions, when the tubular laminated packaging material is transversely ultrasonic sealed. An ultrasonic sealing apparatus, in which a laminated packaging mat...

A sound transducer for the transmission of audio frequency signals with a pressure-voltage transducer is provided. This pressure-voltage transducer is disposed on a supporting plate and at least partially embedded in a sound-insulating, substantially incompressible material, for example a gel. The supporting plate rests herein in contact on a body part, for example a jaw or skull bone, of a person...

PROTEÍNAS DE UNIÓN, Y EN PARTICULAR, ANTICUERPOS HUMANIZADOS QUE PUEDEN USARSE, POR EJEMPLO, EN EL DIAGNÓSTICO, EL TRATAMIENTO Y LA PREVENCIÓN DE LA ENFERMEDAD DE ALZHEIMER Y CONDICIONES RELACIONADAS.; The present invention relates to binding proteins and, in particular, humanized antibodies that may be used, for example, in the diagnosis, treatment and prevention of Alzheimer's Disease and relate...

The present invention relates to human, humanized monoclonal antibodies and to monoclonal antibodies with decreased immunity and to uses and methods of production thereof. The present invention in one aspect in particular relates to polypeptides that have specific sequences and that can be part of antibodies.

Single-chain molecule (I) that binds multiple antigens comprises two variable domains of heavy immunoglobulin chains (VH), having specificities A and B and two variable domains of light chains (VL), also with specificities A and B. The domains are provided as two VH-VL constructs which are attached via a peptide (P). Any VH and VL may be replaced by their functional fragments. Independent claims a...

The present invention provides a human antibody against blood coagulation factor VIII (hereinafter also referred to as "FVIII") and an antibody fragment that binds to human FVIII and specifically inhibits the coagulation activity of human FVIII. ScFv display phage libraries, prepared by using scFv DNAs constructed by random combinations of immunoglobulin VH chain genes and VL chain genes from lymp...

The phenomenon of caking of hygroscopic particulates is analyzed. Mechanical reconditioning of agglomerated material does not prevent the problem of caking to reoccur, either in bags or other storage areas. Percolation of dry air in the bulk hall utilizes the prolonged residence time in the bulk hall to improve the handling quality of the product once and for all. A simple grid arrangement (3) at ...

A method for installing a structure between a first mounting point and a second mounting point. The method involves placing a centering mandrel with a laser positioning unit into a channel in the first mounting point for the structure and locking the centering mandrel in the channel in the first mounting point. The centering mandrel has a first center and the channel has a second center aligned wi...

A method of highlighting a selected object in a 3D scene comprises: executing an off screen rendering software and, responsive thereto, generating a texture image containing an image of the visible parts of a selected object over a background color, and, in response to said texture image, executing an on screen rendering software in combination with a fragment shader software thereby drawing a sil...

A lid (10) e.g. for a food container, consists of a carrier material (5), a printed section and a sealing layer with a shoulder region (4). The lid has a printed pattern on the inside and/or outside, and the pattern (11) has a thickness of 2-20 mu m.

Non-planing vessel with single hull ( 2 ). A foil ( 10 ) is fitted below the waterline at the place where the greatest flow constriction exists, in other words at the transition from the relatively broad part ( 9 ) to the narrowing part. This foil is situated at a distance from the hull ( 2 ) and preferably extends horizontally over as large a part of the hull as possible at a constant distance fr...

A polymer composition, especially used for manufacturing screw caps intended for drinks bottles, which are easy to unscrew and at the same time avoid transmitting a taste and/or a smell to the drinks contained in the bottles. The composition includes (1) a polymer, except a polymer based on a conjugated diene, (2) at least one stabilizer and (3) at least one additive in an amount form 0.01 to 1% b...

The invention relates to an ALD reactor (1 ) for treating one or more substrates (2), the ALD reactor (1 ) comprising at least one reaction chamber which comprises a front plate (6) including gas connections (10) for introducing starting materials, flushing gases and the like gases into the reaction chamber. In accordance with the invention, the front plate (6) is arranged for being placed over th...

An anti-foaming degassing device for use in fuel dispensing equipment, having: a circulating pump (1) for the fuel, a vortex degassing enclosure (2) connected to the outlet of the pump (1) and provided with a lateral outlet pipe (8) for the degassed fuel and with an axial outlet pipe (9) for a gas-enriched fraction of fuel, a separating vessel (3) connected to the axial outlet pipe (9) in which th...