Dosage regimens of buprenorphine to treat withdrawal or abstinence syndrome in a drug dependent or opioid tolerant patient who is pregnant are described. The method includes treating withdrawal or abstinence syndrome of the patient by transdermal administration of an amount of buprenorphine effective to reduce withdrawal symptoms. For example, a first buprenorphine-containing transdermal dosage fo...

Antagonists of alpha4 integrin/alpha4 integrin ligand adhesion, which inhibit the biological effects of such adhesion are described and methods for their use are detailed. Such antagonists are useful in suppressing bone destruction associated with multiple myeloma. The homing of multiple myeloma cells to bone marrow and their alpha4 integrin-dependent release of bone-resorbing factors, resulting i...

An arrangement of one or more structural elements (3) in a cell lining, in particular for use as a side lining in aluminum electrolysis cells (5). The design of and choice of materials for side linings can be fitted in existing electrolysis cells, plus the design and production of the stated material is selected in view of the main purpose of the material, which is to utilize it for the purpose of...

Fluoro substituted cycloalkanoindole derivatives are antagonists of formula I are antagonists of prostaglandins, and as such are useful for the treatment of prostaglandin mediated diseases.

The following are claimed: (A) anthracycline compounds of formula Q-O-R-P (I) Q = a group of formula (i):R = H (sic) or C(O)-(CH2)n-C(O);n = 0-7;R' = NH2; or an aromatic or hydrogenated 5 or 6 membered heterocycle having at least one ring nitrogen, optionally having a butadiene moiety bonded to adjacent carbon atoms to form a bicyclic system;P = H or a peptide; Provided that: (a) where R' is NH2, ...

A trawl door (20, 60) or a paravane (120, 140) having at least one main deflector (22, 22U, 22L) includes a permeable structure disposed adjacent to and separated from an outer surface (34) of the main deflector (22, 22U, 22L). The permeable structure extends from near a trailing edge (26, 26U, 26L) of the main deflector (22, 22U, 22L) over and separated from the outer surface (34) toward the main...

Purified and isolated DNA molecule (I) having the 2566, 2084, 2303 or 1795 bp nucleic acid sequence given in the specification, is new.

A method of interfering with quorum sensing regulation of genes to promote cell growth is disclosed. The method of is aimed at accessing microbial biodiversity. The method involves obtaining a sample from a human comprising at least one novel (uncultivated in the laboratory) microorganism, contacting the sample with an effective amount of an agent or combination of agents which interferes with the...

A fish cage having one or more air-tight buoyancy rings (1) being entirely or partially hollow, with water valves (20) for inlet and outlet of water, and air valves (3) for injection and outlet of air, and preferably with closing shot plates (2) in the buoyancy ring (1). The novel feature according to the invention is that at least one or more of the air valves (3), and preferably also the water v...

A topical pharmaceutical preparation for administering a slightly soluble PDE 4 inhibitor is described. A surprisingly good systemic bioavailability is observed with this dosage form.

A crystal for oral solid medicament comprised of indoline compound (KMD-3213) which exerts alpha 1-adrenaline receptor blocking effect, is useful as a therapeutic agent for dysuria and is represented by the formula: (I) wherein in the powder X-ray diffraction pattern, the compound is characterized by main peaks of 5.5 DEG +/- 0.2 DEG , 6.1 DEG +/- 0.2 DEG , 9.8 DEG +/- 0.2 DEG , 11.1 DEG +/- ...

Methods and systems for hydroprocessing heavy oil feedstocks to form an upgraded material involve the use of a colloidal or molecular catalyst dispersed within a heavy oil feedstock, a hydrocracking reactor, and a hot separator. The colloidal or molecular catalyst promotes hydrocracking and other hydroprocessing reactions within the hydrocracking reactor. The catalyst is preferentially associated ...

The present invention provides a photosensitive resin composition and a resin film obtained from the photosensitive resin particularly useful for a buffer coating material for LSI chips. For this purpose, there are used a photosensitive resin composition, comprising: 100 parts by weight of a polycondensate obtained by condensation-polymerizing compounds represented by specific chemical formulas in...

A method and system for the spray application of epoxy materials is provided. The system includes a dual walled tank structure as a reservoir for containing and preheating the epoxy materials in preparation for mixing and spray application. Each component of the epoxy material is preheated before the components are mixed. After preheating, the components are then mixed together and spray applied. ...

An apparatus and a method for the submicronization of proteins using supercritical fluids is provided for feeding the supercritical fluid and feeding a protein solution using a precipitation vessel with a taper shape at its lower part, in which the precipitation vessel accommodates the supercritical fluid and the protein solution to generate submicroparticles of the protein, and a spray nozzle wit...

A network includes a first network function having an address. There is a second network function requiring the address of the first network function. A third network function is arranged to insert the address of the first network function into a message. A fourth network function is sent the message by the third network function and the fourth network function is arranged to extract the address a...

Embodiments of a fluid storage and introduction device 20 constructed in accordance with aspects of the present invention are provided. One embodiment of the device 20 includes an inner assembly 24 and an outer housing 26 . When assembled, the device 20 is securely coupled to a cable or cable section 30 along a portion of its span. In use, the device 20 is capable of storing remediation fluid and ...

Cloth designed to be provided with at least one permanent fold, wherein at least one shrink thread is woven in said cloth. The shrink thread or shrink threads are woven in the cloth according to a general direction extending crosswise over the fold line.

Provided is a low friction, self-lubricating sleeve for use with a reciprocating piston in the compressor and/or the expander subsystem of a cryogenic cooler or other compressor type system. The sleeve is bonded to an outer surface of the piston, thereby positioning the sleeve between the piston and an inner wall of a piston cylinder. The sleeve is manufactured using a polyetheretherketone base ma...