A 2-arylindole compound substituted in position 5, of formula (I) in which Z, Y, X, W, R, R1 and A have the meanings given in the description; method for its production and an intermediate compound to realize the method; said compounds represent mPGRS-1 inhibitors and compositions containing them are used for treatment of diseases caused by mPGRS-1.

A sole has a supporting layer 10, 110, which, macroportion 11, 111 is made of net, felt or other diffusely perforated material, a membrane 13, 113 made of a material that is impermeable to water and permeable to water vapor is associated at least in the macroportion, a tread 15, 115 made of plastic material, with at least one through macroperforation 16, 116 at the macroportion. The tread is joine...

A device has a container 5 sealed with a cap suitable for storing shaped bodies, a dispensing opening 35, and means forwarding the shaped bodies from the inside of the container to the dispensing opening, with this, the container is capable to move in a house 1 as a piston against elastic returning force. The dispensing opening is situated in the bottom 2a of the house; when the device is in a pos...

Ointment contains an oil extract on an olive oil of flowers horse gowan Matricaria chamomilla L., flowers of calendula medicinal Calendula officinalis L., a terraneous part of St.-John's wort Hypericum perforatum L., leaves of eucalyptus Eucalyptus, leaves of bur-marigold Bideus tripartite L., leaves of sage Salvia officinalis L., leaves of coltsfoot Tussilago farfara L., and an oil extract on a s...

A construction contains a wall raised across the river-bed 1, the wall being made of two parts, one part 2 of which is stepwise, and the second part 3 is raised from hollow blocks 4 and cavities are filled with crushed stones, the stepwise wall is executed from ferro-concrete and in the scheme has the form of a broken line so, that the height of the sites located across the stream are greater than...

A device contains a block 1 for thermolysis, which by an electricity cable 2 is connected with a threaded tube 3. The tube is pasted in the first part 4 of the handle consisting of two parts, the second part 5 of the handle has a thread for screwing on the tube and an aperture 6 for fastening a needle 7, in the second part of the handle a needle-holder 8 is placed. The device contains an air compr...

A structure contains established on the prepared on the basis ground the blocks 3, 4 and 8, which are concreted with the ledges of the reinforcement incorporated in slab 1 established on the basis or foundation framework 2, the blocks in the scheme has the form of an equilateral triangle or the form of parabolic segments and are located on all the length of a slab by the vertexes, directed opposit...

A crib contains a support frame 1, a part 2 for lying established thereon with an opportunity of vibratory movement, on which from the bottom side the constant magnet 3 is fixed, under which, on a frame the electromagnet 4 connected by means of the control package 5 with power supply is fixed. The crib has the sensing transducer of an initial position of the part for the lying, connected with the ...

The invention relates to a method for processing credits to be used by subscribers of communications networks, subscribers of mobile and other communications. The method provides obtaining a credit by sending a conditional request, automatic checking the creditworthiness, processing the saved balance data of the client, depositing the amount to the balance, when depositing additional amounts, auto...

Subject: integrated electronic system meant for the remote control of vehicles (for the location and identification of non-insured and so illegally circulating vehicles). Constitution: electronic radio frequency identification circuits 1, Radio Frequency Identifiers (RFID), a local computer network 14, readers 9, 10, 11 and printing-programming devices 22 (RFID) and a central database 15 for the o...

A transistor includes a semiconductor channel disposed nearby a gate and in an electrical path between a source and a drain, wherein the channel and at least one of the source or the drain are separated by an interface layer so as to form a channel-interface layer-source/drain junction in which a Fermi level of the semiconductor channel is depinned in a region near the junction and the junction ha...

Nucleic acids encoding mammalian, e.g., primate, receptors of OX2, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Method of using the compositions for both diagnostic and therapeutic utilities are described.

A system and method for performing topology control in a wireless network ( 100 ). The system and method operate to enable a node ( 102 - 1 ) to determine the link cost of a link between itself and another node ( 102 - 2 ), based on the number of nodes ( 102, 106, 107 ) that would be affected by message transmission by the node ( 102 ) and the other node ( 102 - 2 ), and the number of nodes ( 102,...

The procedure consists of phosphatising the sludge, preferably with phosphoric acid at a rate of under 15 per cent, depending on the heavy metal content, and then causing it to foam by the addition of chemical reagents or mechanical agitation to reduce its density to less than 90 per cent of its original density. The foam is dried by existing composting techniques, e.g. in a tunnel with a bed of ...

A controlling device for controlling lighting parameters is connected to a number of lamps and includes a controlling member which is placed on a contact surface by a user. Lighting parameters of each lamp are determined based on the position of the controlling member on the contact surface. This enables the user to control the lighting parameters simply by controlling the position of the controll...

A consumer electronics device makes content available and include a control unit and a transmitter. The control unit is able to create a representation of a human perceptual signal and instruct the transmitter to broadcast the representation. The device is able to access new content via a receiver. The control unit uses the receiver to receive representations of multiple further human perceptual s...

An apparatus comprising a first cell ( 10 b), said first cell comprising a plurality of first elements ( 34 b), said first elements being controllable between a non-reflective state, in which electromagnetic radiation having a first polarization is reflected to a first extent, and a reflective state, in which said electromagnetic radiation having a first polarization is reflected to a second exten...

The mass has a mass unit with a center of gravity (G) displaced with respect to an axis of rotation defined by a bearing (12). The mass unit has two detachable parts (10, 18) placed in such a way that the relative displacement produces a radial displacement of the center of gravity. A fixing unit (16b) cooperates with the parts so that the parts are displaced with respect to each other and rigidly...

An electronic sphygmomanometer includes an activation controlling part (201) for performing a control to activate one of a plurality of functions (203 to 206) included in a first function group and a second function group of the electronic sphygmomanometer based on an instruction signal from a user. The first function group includes a measuring function (203, 204) by a blood pressure measuring uni...