A humanized anti-NGF antibody or a fragment thereof which maintains binding activity to NGF, wherein the humanized anti-NGF antibody comprises, (a) a VH region having a first CDR comprising the amino acid sequence GFSLTNNNVNW, a second CDR comprising the amino acid sequence GVWAGGATDYNSALKS, and a third CDR comprising the amino acid sequence DGGYSSSTLYAMDA; and (b) a VL region having a first CDR...

Procedure to obtain multilayer coatings with high wear resistance, in particular for light alloy metal materials and for metal matrix composite materials, wherein the material to be coated is subjected to the following operations: a) surface deposition, using thermal spray techniques, of a first cermet coating, with thickness ranging from 20 to 600 µm; b) surface finishing treatment; c) deposition...

An electro-thermal actuator device comprises a case defining a cavity in which are housed a thermal actuator, an electrical heater and, at least partially, an actuating shaft. The device comprises a multipolar connector for the rapid, secure and reliable coupling to a respective source of electrical power supply for the heater. The connector can be configured as an adapter unit distinct from the c...

Wheel hub-bearing unit (1) for a vehicle presenting a central cylindrical housing for the insertion of a semi-axis (A) of the vehicle, and a rotating bearing (10) which presents an inner side (L1) and an outer side (L2) , and which is provided wi th an inner race (12) which defines the cylindrical housing (2), and with an outer race (13) which is integral with the fixing flange (3) and which is co...

The combustor (1) comprises a stationary structure (2), and at least one annular rotor supported rotatably about a shaft (4) by contactless suspension means (5-8). The rotor (3) comprises a first and a second main annular portions (3', 3'') which are interconnected by an intermediate annular portion (103) and in each of which there is defined a combustion chamber (20', 20'') that has a directed la...

The combustor (1) comprises a stationary structure (2) and at least one tubular annular rotor (3) able to rotate about a shaft (4) by means of contactless suspension devices (5-8), and in which is defined an annular combustion chamber (20) having a directed lateral efflux opening (21, 23) for the ejection of gases produced in the combustion. The rotor (3) has a narrow circular slit (30) throug...

The electricity generator (1) comprises a microcombustor (2) provided with a fuel injector (3) and acting to produce at an exhaust outlet (5) a flow of exhaust gas in plasma state comprising positive ions and electrons separated from one another, and a conversion device (6) coupled to the outlet (5) of the microcombustor (2). The conversion device comprises an electrically insulating duct (7) coup...

A pneumatic operating device (6) for direct braking and an electropneumatic valve unit (10) of an anti-slip device have their outlets connected to the braking actuators (3) through an interlock valve device (20) which can selectively allow the greater of the pressures received from the said devices (6, 10) to pass towards the braking actuators (3). The electrical operating device (7) for the dire...

The combustor (1) comprises a stationary structure (2; 102) and at least one tubular rotor (3; 3', 3") supported rotatably about an axis (4) by the structure (2; 102) by means of contactless suspension devices (5-8; 5', 5", 6', 6") there being formed within this rotor at least one combustion chamber (20; 20', 20") having at least one orientated lateral outflow aperture (21; 22; 23, 24) for the eje...

A wearable device for cyclists comprising: an upper shell (61), for application to at least one instep region of a foot or of a shoe; a lower shell (62), for application to at least one region of the foot or of the shoe that lies substantially opposite the instep region; the lower shell (62) being connected to the upper shell (61) in order to form a containment frame for the foot or the shoe; at l...