INHIBIDORES SELECTIVOS DE MMP-13 SON DERIVADOS DEL ACIDO ISOFTALICO DE FORMULA I EN LA QUE: R1, R2 Y R3 SON INDEPENDIENTEMENTE HIDROGENO, HALO, HIDROXI, ALQUILO C1-C6, ALCOXI C1-C6, ALQUENILO C2-C6, ALQUINILO C2-C6, NO2, NR4R5, CN O CF3, E ES INDEPENDIENTEMENTE O o S, A Y B SON INDEPENDIENTEMENTE OR4 o NR4R5, CADA UNO DE R4 Y R5 ES HIDROGENO, ALQUILO C1-C6, ALQUENILO C2-C6, ALQUINILO C2-C6, (CH2)n...

A találmány tárgya eldobható abszorbens cikk, amely tartalmaz: –hátlapot (26), – fedőréteget (24); a hátlap (26) és a fedőréteg (24)között elhelyezett – folyadék elnyelő/eloszlató réteget; – legalábbegy folyadéktároló réteget. A cikk teljes termékelnyelésiteljesítménye több mint 3,75 ml/s az első folyadékkieresztéskor éstöbb mint 0,5 ml/s a negyedik folyadékkieresztés alkalmával, abehajtott termék...

A találmány oxigénadagoló nagynyomású, gázkisülésű lámpákhoz,fémedényben tárolt, oxigénfejlesztő anyaggal, amely fémedényben (11)tárolt oxigénfejlesztő anyag (12) Ag2O. Előnyösen az oxigénfejlesztőAg2O anyag por alakú, szükség szerint inert anyagú porral ésgetteranyaggal kiegészítve. ŕ; It is described an oxygen dispenser for use in high pressure discharge lamps. The oxygen dispenser of the invent...

The tread of a heavy duty pneumatic vehicle tyre has depth indicators (5) at the sections radially under the profile grooves (2). Each depth indicator (5) shows the min. tread depth for an effective road grip, and the max. wear which cannot be exceeded.

Apparatus for carrying out patch clamp technique utilized in studying the effect of certain materials on ion transfer channels in biological tissue, and more particularly patch clamp apparatus utilizing an autosampler, such as those utilized with HPLC apparatus, to provide high throughput, is disclosed. The invention additionally includes novel microperfusion chamber assemblies capable of utilizin...

Apparatus is disclosed for determining at least two outside dimensions of a rectangular package travelling at a known velocity, the package including first and second substantially parallel sides extending the length of the package. The apparatus comprises conveyor means (12), first and second side sensor means (21 and 22), and calculating means (100). The conveyor means (12) moves the package at ...

A centrifuge apparatus which comprises a container (10) including a cylindrical member (11) with a lower rim and a piston member with a tubular piston rod (12). A supporting turntable (1) with a first gripping means (27) releasably grips the lower rim when the container (10) is placed thereon, said supporting turntable (1) being connected with a first activating means (5) for rotating the turntabl...

An improved apparatus for controlling brake force is disclosed. An engine selectively performs a stratified charge combustion and a uniform charge combustion. A brake booster (71) is actuated by negative pressure an absolute value of which is greater than a predetermined magnitude. An electronic control unit (30) actuates the throttle valve (23) to apply the negative pressure to the brake booster ...

The magnetic properties of rare earth magnet are improved by means of forming a novel structure of the cast alloy used for the production of a rare earth magnet, which contains from 27 to 34% by weight of at least one rare earth element (R) including yttrium, from 0.7 to 1.4% by weight of boron, and the balance being essentially iron and, occasionally any other transition element, and comprises an...

Sliding or rolling contacts (12,13) are arranged above and below the fabric (2) to detect excessive sag in the fabric. When the fabric touches a contact, a signal initiates corrective adjustment of the appropriate hot air blowing nozzle. The machine has a housing (3) with a goods path intake (4) on a housing end, and a goods path outlet (5) at the other end.

Production of a porous metal body comprises compacting a mixture consisting of a powdered metallic material containing a metal and/or a metal alloy and a gas-splitting propellant-containing powder to form a semi-finished product; and foaming under the influence of heat. The propellant-containing powder is selected so that the temperature of decomposition is less than 120K below the melting tempera...

Computer tomography method in which the focus is moved along a focus path about a system axis without relative movement between it and the examination object. At the same time a detector system supplies measurement data proportional to the received radiation. The length of the focal path is at least as long as a partial contour interval, the length of which is suitable for completely reconstructin...

Die Vollmantel-Schneckenzentrifuge dient zum kontinuierlichen Trennen eines aus mehreren Phasen bestehenden, fließfähigen Gemisches. Sie hat einen aus einer zylindrischen und einer konischen Trommel zusammengesetzten Rotor (10) mit Austragsöffnungen für die voneinander getrennten Phasen und eine innerhalb des Rotors drehbare Förderschnecke (18) für den Transport der schwersten Phase zu der entspre...

Control of a multi-variable process involves multi-dimensional representatio n of the values (Qa-Qh) of the process variables according to individual coordinate axes (Xa-Xh), and response based on sets of values for the proces s- variables accumulated from multiple, earlier operations of the process. An acceptable range (UL-LL) for each process variable due to the current values of the other varia...

A limited slip differential includes a differential case having a central axis, the differential case being connected to an input shaft of an engine, a drive body coaxially disposed within the differential case, a planetary gear unit disposed around the drive body, a cam assembly for performing a differential action depending on a speed difference generated by planetary gear unit, and a multi-plat...

A catheter system includes an outer catheter having a lumen and an inner catheter sized to fit within and slide through the lumen of the catheter. Both catheters may be introduced into an anatomical site through a single introduction path. At the distal-end region of each catheter is an electrode system. One electrode system is for mapping the site; the other is for ablating the site. The distal-e...

A method of manufacturing tires (1) defined by a number of components (3-16), and wherein at least one mobile tire building unit (56) is moved along a feedpath (PA, PB) extending through a number of work stations (25-32, 35-40) to receive at least one of the work stations (25-32, 35-40) being a programmable work station, wherein the relative component is formed directly on the mobile unit (56) by ...

The process according to the invention relates to the preparation of 2-chloromethyl-thiophene of the formula (I). During this process thiophene is chloromethylated in the presence of one or more compounds containing keto group and optionally it is transforme d into the compound of the formula (II). Compounds of formula (I) and (II) are intermediates of several pharmaceutically active ingredients....

A method of controlling a robot (1102) having detection means (1103, 1104) for detecting an object (1109) in one of a number of zones relative to the robot; and processing means for selecting and performing a predetermined action in response to said detection, the action corresponding to the detected zone. The method comprises presenting to a user via a graphical user interface (1101) a number of ...