NOVEL USES OF CERTAIN PEPTIDES TO TREAT PATIENTS SUFFERING FROM NEUROLOGICAL OR PSYCHIATRIC DISORDERS ARE DISCLOSED. THE PEPTIDES INCLUDE THE TRIPEPTIDE HORMONE MIF AND COMPOUNDS MADE BY MODIFICATIONS OF MIF, SUCH AS MODIFICATION OF AMINO TERMINUS RESIDUES, CARBOXYL TERMINUS RESIDUES AND INTERNAL RESIDUES, INCLUDING ADDITION AND SUBSTITUTION OF AMINO ACID RESIDUES AND MODIFICATION OF THE PEPTIDE B...

A RESEALABLE CAP (110, 210) FOR A MEDICAMENT VIAL (114, 214) HAS A BASE PORTION (112, 212) FORMED OF VULCANIZED RUBBER OR LIKE MATERIAL KNOWN FOR PROVIDING A STABLE ENVIRONMENT FOR THE MEDICAMENT CONTAINED WITHIN THE VIAL, AND A RESEALABLE PORTION (126, 226) OVERLYING THE BASE PORTION. THE RESEA1ABLE PORTION (126, 226) IS MADE OF 10WDENSITY POLYETHYLENE OR LIKE MATERIAL, AND CAN BE PUNCTURED BY A ...

A PROCESS FOR THE SELECTIVE HYDROGENATION OF DIENES IN MIXED STREAMS OF OLEFIN CONTAINING HYDROCARBONS, SUCH AS BUTADIENE IN A MIXED C₄ STREAM WITH MINIMUM LOSS OF MONOOLEFINS IS DISCLOSED WHEREIN THE REACTOR IS OPERATED AT CONDITIONS WHICH INDUCE PULSE FLOW. THE PULSE FLOW IS INDUCED IN A DOWNFLOW BOILING POINT REACTOR BY VAPORIZATION OF A PORTION OF THE LIQUID FEED AT PROPER CONDITIONS.

THE INVENTION RELATES TO THERMALLY CONDUCTIVE GREASES THAT MAY CONTAIN CARRIER OIL(S), DISPERSANT(S), AND THERMALLY CONDUCTIVE PARTICLES, WHEREIN THE THERMALLY CONDUCTIVE PARTICLES ARE A MIXTURE OF AT LEAST THREE DISTRIBUTIONS OF THERMALLY CONDUCTIVE PARTICLES, EACH OF TILE AT LEAST THREE DISTRIBUTIONS OF THERMALLY CONDUCTIVE PARTICLES HAVING AN AVERAGE (D50) PARTICLE SIZE WHICH DIFFERS FROM THE O...

2' AND/OR 3' PRODRUGS OF 6-MODIFIED, 1' 2' 3' OR 4'-BRANCHED PYRIMIDINE NUCLEOSIDES OR 8-MODIFIED, 1', 2', 3' OR 4'-BRANCHED PURINE NUCLEOSIDES, AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND DERIVATIVES ARE DESCRIBED. THESE PRODRUGS ARE USEFUL IN THE PREVENTION AND TREATMENT OF FLAVIVIRIDAE INFECTIONS, INCLUDING HCV INFECTION, AND OTHER RELATED CONDITIONS. COMPOUNDS AND COMPOSITIONS OF THE PRODR...

AN IMPROVED PROCESS FOR MANUFACTURE OF (E)-7-[4-(FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL)METHLSULFONYL)AMINO]PYRIMIDIN -5-YL](3R,5S)-3,5-DIHYROXYPHEYPT-6-ENOIC ACID CALCIUM SALT (1), WHICH IS USEFUL FOR THE PRODUCTION OF A PHARMACEUTICAL USEFUL IN THE TREATMENT OF, INTER ALIA, HYPERCHOLESTEROLEMIA, HYPERLIPOPROTEINEMIA AND ATHEROSCLEROSIS, IS DESCRIBED.

THERE IS PROVIDED A PROCESS FOR MAKING NON-OIL-FRIED, FILLED SNACKS THAT KEEP LONGER,ARE PALATABLE, ATTRACTIVE, AND ASSURE GOOD SHAPE RETENTION, THEREBY PRESENTING HIGH COMMERCIAL VALUE. THE PROCESS FOR MAKING FILLED SNACKS AS DRIED BY NON-OIL- FRYING COMPRISES THE STEPS OF KNEADING A WHEAT FLOUR MIXTURE TO PREPARE DOUGH, ROLLING SAID DOUGH TO PREPARE A DOUGH SHEET, STEAMING SAID ROLLED DOUGH SHEE...

THE PRESENT INVENTION PROVIDES A PRECOATED METAL SHEET, FOR LIGHT REFLECTORS, HAVING A HIGH DIFFUSE REFLECTANCE OF VISIBLE LIGHT, AND ALSO PROVIDES THE ELECTRIC OR ELECTRONIC APPARATUS USING IT. THE PRECOATED METAL SHEET COMPRISES A METAL SHEET OR PLATED METAL SHEET (1), A VISIBLE LIGHT REFLECTIVE UNDERCOAT (2) HAVING A THICKNESS OF 3 TO 30 MICROMETERS PROVIDED ON AT LEAST ONE SURFACE OF THE METAL...

THE PRESENT INVENTION RELATES TO A PROPELLANT-GAS-FREE APPARATUS FOR THE DISPENSING OF LIQUIDS, A CONTAINER CARTRIDGE (10) SUITABLE FOR THIS FOR STORING THE LIQUID AND THE ENSEMBLE COMPRISING BOTH. THE INVENTION COMPRISES A DEVICE FOR THE EXERTION OF PRESSURE AND FOR ACCOMMODATING A CONTAINER CARTRIDGE (10) AND A CONTAINER CARTRIDGE IN WHICH THE DISPENSING FACILITY (29) IS INTEGRATED.

IT IS AN OBJECT OF THIS INVENTION TO PROVIDE A METHOD FOR PRODUCING AN ESTER BY A TRANSESTERIFICATION REACTION IN WHICH THE REACTION CAN BE STABLY PERFORMED IN A SHORT TIME AT A PRESSURE APPROXIMATELY EQUAL TO NORMAL PRESSURE. THE ESTER IS PRODUCED BY A TRANSESTERIFICATION REACTION IN WHICH A STARTING MATERIAL ESTER AND AN ALCOHOL ARE BROUGHT INTO CONTACT WITH A SOLID ACID CATALYST THAT DISPLAYS T...

A GLASS OR OTHER SILICA CONTAINING SURFACE IS MASKED OR STENCILED OFF RANDOMLY OR IN A SPECIFIC PATTERN OR DESIGN AND TREATED WITH A LIQUID OR VAPOR CHEMICAL COMPOSITION THAT RANDOMLY OR BY SPECIFIC PATTERN FILLS IN THE MICROSCOPIC VALLEYS AND PITS FOUND IN ALL TYPES OF GLASS AND SILICA CONTAINING SURFACES, IMBEDDING THAT RANDOM OR SPECIFIC PATTERN (IMAGE) INTO OR ONTO THE SUBSTRATE. AS THE GLASS ...

THE PRESENT INVENTION RELATES TO SUBSTITUTED PYRAZOLINE COMPOUNDS, METHODS FOR THEIR PREPARATION, MEDICAMENTS COMPRISING THESE COMPOUNDS AS WELL AS THEIR USE FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF HUMANS AND ANIMALS.

A PROCESS FOR PRODUCING BRANCHED OLEFINS FROM A MIXED LINEAR OLEFIN/PARAFFIN ISOMERISATION FEED COMPRISING LINEAR OLEFINS HAVING AT LEAST 7 CARBON ATOMS IN 5-50%W COMPRISING IN A FIRST STAGE SKELETALLY ISOMERISING LINEAR OLEFINS IN THE ISOMERISATION FEED AND IN A SECOND STAGE SEPARATING BRANCHED AND LINEAR MOLECULES WHEREIN BRANCHED MOLECULES ARE SUBSTANTIALLY OLEFINIC AND LINEAR MOLECULES ARE OLE...

THE PRESENT INVENTION RELATES TO ONCOLYTIC ADENOVIRUSES HAVING THERAPEUTIC APPLICATIONS. RECOMBINANT CHIMERIC ADENOVIRUSES, AND METHODS TO PRODUCE THEM ARE PROVIDED. THE CHIMERIC ADENOVIRUSES OF THE INVENTION COMPRISE NUCLEIC ACID SEQUENCES DERIVED FROM ADENOVIRAL SEROTYPES CLASSIFIED WITHIN THE SUBGROUPS B THROUGH F DEMONSTRATE AN ENHANCED THERAPEUTIC INDEX.

THE PRESENT INVENTION PROVIDES COMPOUNDS OF FORMULA (I) WHEREIN ( ) IS AN OPTIONAL ETHYLENE BRIDGE; R1 IS ALKYL, CYCLOALKYL, ARYL OR ARYL SUBSTITUTED WITH ONE OR MORE SUBSTITUENTS SELECTED FROM ALKYL, ALKOXY AND AMINO, OR R1 IS PYRIDYL OR PYRIDYL SUBSTITUTED WITH ONE OR MORE SUBSTITUENTS SELECTED FROM ALKYL, ALKOXY AND AMINO; R2 IS OPTIONALLY SUBSTITUTED ALKYL, ALKOXYALKYL, OPTIONALLY SUBSTITUTED ...

A LIQUID STATE BIOCONVERSION (LSB) PROCESS FOR TREATING STP SLIDGE HAVING THE STEPS OF PROVIDING SLUDGE AT A DESIRED RATE, MIXING THE SLUDGE WITH MIXED FUNGI, ADDING CARBOHYDRATE AS NUTRIENT SOURCE INTO THE MIXTURE AND CONTROLLING THE MIXED FUNGI ACTIVITY IN THE MIXTURE IN A BATCH FERMENTER UNDER SUITABLE CONDITION TO ENCHANCE THE BIODEGRADATION, BIOSEPARATION AND BIOSOLIDS ACCUMULATION OF THE SLU...

THIS INVENTION RELATES TO NOVEL DIARYL UREAS, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS AND THE USE OF THOSE COMPOUNDS OR COMPOSITIONS FOR TREATING HYPER-PROLIFERATIVE AND ANGIOGENESIS DISORDERS, AS A SOLE AGENT OR IN COMBINATION WITH CYTOTOXIC THERAPIES.

BIODEGRADABLE POLYOL ESTERS DERIVED FROM BRANCHED POLYOL HAVE BEEN DEVELOPED FOR VARIOUS BIODEGRADABLE LUBRICANT APPLICATIONS. THESE FLUIDS HAVE EXCELLENT THERMAL STABILITY, BETTER LUBRICITY, LOW VOLATILITY AND RESIST HYDROLYSIS BETTER THAN OTHER ESTERS. WITH PROPER ADDITIVE, POLYOL ESTERS ARE MORE OXIDATIVELY STABLE THAN THE OTHER SYNTHETIC FLUIDS. AS A RESULT OF EXTENSIVE STUDIES, PALM OIL METHY...

DISCLOSED ARE SMALL PELLETS OR "MINI-DRAGÉES" WITH A CORE CONSTITUTED BY A GUM BASE WHICH IS FLAVORED AND POSSIBLY SWEETENED WITH HIGH-INTENSITY SWEETENERS, AND FORMULATED WITHOUT THE SUGARS OR POLYOLS CONVENTIONALLY USED IN THE MANUFACTURE OF TRADITIONAL CHEWING GUMS.

THIS INVENTION RELATES TO COMPOUNDS WHICH ARE GENERALLY MUSCARINIC M2/M3 RECEPTOR ANTAGONISTS AND WHICH ARE REPRESENTED BY FORMULAWHEREIN X, Y, AND Z ARE -0-, -8- OR >N-R5, AND THE OTHER SUBSTITUENTS ARE AS DEFINED IN THE SPECIFICATION; OR PRODRUGS, INDIVIDUAL ISOMERS, RACEMIC OR NON- RACEMIC MIXTURES OF ISOMERS, AND PHARMACEUTICALLY ACCEPTABLE SALTS OR SOLVATES THEREOF. THE INVENTION FURTHER RELA...