(-)-Cis-4-amino-1- (2-hydroxymethyl-1,3 -oxathiolan-5-yl)-(1H)- pyrimidin-2-one (I) and its derivs. are new. (I) contg. max. 5 wt% of (+)-enantiomer (pref. below 1 wt%) is also claimed. (I) is prepd. by sepn. from a racemic mixt., preferably by chiral HPLC. The stationary phase used is preferably beta-cyclodextrin or cellulose triacetate. Alternatively sepn. is by enzyme-mediated enantioselective ...

A leadfree plate-shaped roof flashing material comprises a sandwich structure in which a stress damping and stabilizing layer (1) of ductile material is completely covered on one side and at least partly covered on the other side by preferably metallic foil sheetings (2, 3), e.g. of aluminium foil, designed with densely positioned flattened folded sections (4) having such a form, e.g. as closed in...

Anchoring cartridge for a hardening multi-component material (I), with a mixt. of a radically-cured resin (II) and fillers (A) in the inner cartridge and a hardener component (B) in the annular space between inner and outer cartridge, the system being activated by driving an anchor bar into the borehole contg. the cartridge. The annular space has an inner dia. equal to at least the wall thickness ...

The present invention called Blind Folks Mobile, BFM, deals with bi-energy vehicles, mainly human powered and mobilized by the folks riding them, using: (A) three wheel lightweight, portable vehicles, foldable and convertible to other utilities, with built in standby motors, accommodating five passengers or more, all contributing individually to mobilize said vehicles; (B) four wheel vehicles adap...

PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.

The invention relates to the use of complexes and chelates resp., of antibiotics, especially azithromycin, with bivalent and/or trivalent metals in the obtaining of antiulcer drugs, to new complexes and chelates resp., of antibiotics with bivalent and/or trivalent metals and to processes for the obtaining thereof.

PCT No. PCT/DK90/00077 Sec. 371 Date Sep. 20, 1991 Sec. 102(e) Date Sep. 20, 1991 PCT Filed Mar. 19, 1990 PCT Pub. No. WO90/11283 PCT Pub. Date Oct. 4, 1990.A process for the preparation of 9-substituted quanine derivatives of general formula (I), in which R is C1-C4-alkyl optionally substituted with one or more hydroxy groups, or R is ( alpha ), benzyl, ribosyl, 2'-deoxyribosyl or (CH2)n-OR1 wher...

The invention relates to 9a-N-(N'-carbamoyl) and 9a-N-(N'-thiocarbamoyl) derivatives of 9-deoxo-9a-aza-9a-homoerythromycin A, novel semisynthetic macrolide antibiotics of the azalide series, of the formula (I) wherein R represents a C1-C3 alkyl, aryl or aralkyl group and X represents O or S, and pharmaceutically acceptable addition salts thereof with inorganic or organic acids, to the inter...

The present invention refers to the new compounds of formula (I) of the secomacrolide and secoazalide class, a process for the preparation thereof as well as to new intermediates of formula (II) for the preparation of these seco derivatives.

Erythromycin derivs. of formula (I) and their acid addn. salts are new: wavy line indicates 10(R) or 10(S) methyl; R1, R2 = H or up to 24C opt. unsatd. hydrocarbyl (opt. interrupted by 1 or more heteroatoms and opt. carrying 1 or more functional gps.); or R1 + R2 = a heterocycle, opt. with 1 or more additional heteroatoms (N, O and/or S); or R1 + R2 = a gp. of formula (i); R1', R2' = H or up to 23...

A process for producing chlorosulfate and sulfamate esters of 2,3:4,5-bis-O-(1-methylethylidene)- beta -D-fructopyranose and (1-methylcyclohexyl)methanol is disclosed. The process involves a two step procedure involving in the first step reacting of an alcohol with sulfuryl chloride in the presence of a tertiary or heterocyclic amine base in a solvent selected from the group consisting of toluene,...

Solidifying a cover onto a shaped padding, by gluing, involves arranging a cover (1) in a cold shape (2) and holding it by a frame (3), then applying a glue (4) onto the internal walls of the cover, heating the surface of the padding (5) and immediately applying the heated foam padding to the glued walls of the cover, to give immediate transfer of heat by direct contact and very rapid hardening of...

An absorbent article such as a sanitary napkin, having flaps and a recessed area wherein the flaps may be tucked.

PCT No. PCT/BE95/00108 Sec. 371 Date May 27, 1997 Sec. 102(e) Date May 27, 1997 PCT Filed Nov. 23, 1995 PCT Pub. No. WO96/16917 PCT Pub. Date Jun. 6, 1996A process for producing a crystalline siliceous refractory mass includes providing particulate constituents to be projected comprised of (1) solid refractory particles comprising silica in the form of vitreous silica, and (2) solid combustible pa...

A device is claimed for improving the insertion and replacement of a casting tube of a metal casting vessel in which a stopper plate and/or replaceable casting tube inserted in a moving plate is juxtaposed with a common transverse edge against a moving plate carrying a replacement casting tube or against a stopper plate remote from the casting hole. The moving plates are mounted to slide on guide ...

An article of manufacture is disclosed for absorbing liquids, particularly body fluids such as menses. The disclosed article is disposable and has a wrapper associated therewith. An elastic material is secured to the backsheet and is maintained in a substantially tensioned state until separation of the wrapper from the backsheet. Upon separation of the wrapper from the backsheet the tension in the...

Crystalline spirostanyl glycosides and processes for making them are disclosed. The crystalline spirostanyl glycosides are useful for treatment of hypercholesterolemia or atherosclerosis.

Pyrazoles of formula (I) are new. In (I), R1 = CN, NO2, halo, formyl, alkycarbonyl or cycloalkylcarbonyl; R2 = halo, alkyl, haloalkyl, alkoxy, haloalkoxy, NO2, thiocyanate, (or optd. mono- or di-alkyl substd.) sulphamoyl, or aminocarbonyl, alkoxycarbonyl or opt. substd. R9S(O)n; n = 0 to 2; R9 = alkyl, haloalkyl, cycloalkyl, halocycloalkyl, cyclo-alkyl- alkyl or halocycloalkyl alkyl; R3 = H, alkyl...

The invention relates to the reception of fibers under fibering machines to obtain a mat of mineral wool. It proposes assigning to each fibering machine its own collecting zone, the surfaces of the collecting zones increasing in the direction of the increase of base weight. The invention also proposes a device characterized by the presence of two reception drums for three fibering machines.