The present invention relates to a digital interactive communication system accessible to a plurality of subscribers who can select by means of their touch-tone telephones any of a plurality of pre-recorded video presentations representative of products and services for sale. In this system, the subscriber requests are received by a voice network interface which is coupled to a local area network....

The present invention relates to a digital interactive communication system accessible to a plurality of subscribers who can select by means of their touch-tone telephones any of a plurality of pre-recorded video presentations representative of products and services for sale. In this system, the subscriber requests are received by a voice network interface which is coupled to a local area network....

The present invention relates to a digital interactive communication system accessible to a plurality of subscribers who can select by means of their touch-tone telephones any of a plurality of pre-recorded video presentations representative of products and services for sale. In this system, the subscriber requests are received by a voice network interface which is coupled to a local area network....

The present invention relates to a digital interactive communication system accessible to a plurality of subscribers who can select by means of their touch-tone telephones any of a plurality of pre-recorded video presentations representative of products and services for sale. In this system, the subscriber requests are received by a voice network interface which is coupled to a local area network....

Phosphorus-contg. derivs. of 4'-demethyl epipodophyllotoxin glucosides of formula (I) and pharmaceutically acceptable salts are new, where R1 and R6 together complete a 5-6C cycloalkyl gp.; or R1, R6 = 1-8C alkyl; or R6 = H; and R1 = 1-10C alkyl, 2-10C alkenyl, 5-6C cycloalkyl, 2-furyl, 2-thienyl, 6-10C aryl, 7-14C aralkyl or 8-14C aralkanyl, where the aromatic rings are opt. substd. by halogen, 1...

Phosphorus-contg. derivs. of 4'-demethyl epipodophyllotoxin glucosides of formula (I) and pharmaceutically acceptable salts are new, where R1 and R6 together complete a 5-6C cycloalkyl gp.; or R1, R6 = 1-8C alkyl; or R6 = H; and R1 = 1-10C alkyl, 2-10C alkenyl, 5-6C cycloalkyl, 2-furyl, 2-thienyl, 6-10C aryl, 7-14C aralkyl or 8-14C aralkanyl, where the aromatic rings are opt. substd. by halogen, 1...

Phosphorus-contg. derivs. of 4'-demethyl epipodophyllotoxin glucosides of formula (I) and pharmaceutically acceptable salts are new, where R1 and R6 together complete a 5-6C cycloalkyl gp.; or R1, R6 = 1-8C alkyl; or R6 = H; and R1 = 1-10C alkyl, 2-10C alkenyl, 5-6C cycloalkyl, 2-furyl, 2-thienyl, 6-10C aryl, 7-14C aralkyl or 8-14C aralkanyl, where the aromatic rings are opt. substd. by halogen, 1...

Phosphorus-contg. derivs. of 4'-demethyl epipodophyllotoxin glucosides of formula (I) and pharmaceutically acceptable salts are new, where R1 and R6 together complete a 5-6C cycloalkyl gp.; or R1, R6 = 1-8C alkyl; or R6 = H; and R1 = 1-10C alkyl, 2-10C alkenyl, 5-6C cycloalkyl, 2-furyl, 2-thienyl, 6-10C aryl, 7-14C aralkyl or 8-14C aralkanyl, where the aromatic rings are opt. substd. by halogen, 1...

A medical device which can be introduced into the body tissue of a human or animal comprises a matrix of a polyurethane elastomer with organic silicone polymer units built into the main polymer chain and an oligodynamic agent spatially distributed uniformly within the matrix. The oligodynamic agent releases bacteriocidal or microbicidal metal ions when exposed to body tissues. The method for manuf...

A medical device which can be introduced into the body tissue of a human or animal comprises a matrix of a polyurethane elastomer with organic silicone polymer units built into the main polymer chain and an oligodynamic agent spatially distributed uniformly within the matrix. The oligodynamic agent releases bacteriocidal or microbicidal metal ions when exposed to body tissues. The method for manuf...

This invention relates to a novel method for the delivery of cytotoxic drugs to tumor cells by the administration of a tumor-specific antibody-enzyme conjugate that binds to the tumor cells, and the additional administration of a prodrug that is converted at the tumor site, in the presence of the antibody-bound enzyme, to an active cytotoxic drug. According to preferred embodiments of this inventi...

This invention relates to a novel method for the delivery of cytotoxic drugs to tumor cells by the administration of a tumor-specific antibody-enzyme conjugate that binds to the tumor cells, and the additional administration of a prodrug that is converted at the tumor site, in the presence of the antibody-bound enzyme, to an active cytotoxic drug. According to preferred embodiments of this inventi...