Processes of the present invention provide economical methods for preparing derivatives 5-C-hydroxymethyl-D-aldohexose and their bicyclic anhydro tautomeric forms. The 5-C-hydroxymethylation process comprises an enzymic oxidation reaction followed by a condensation reaction with formaldehyde.

7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are =O, =S, =Se and =NCN. Compositions and methods of use are also disclosed.

7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are heteroatom-substituted-hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are =O, =S, =Se and =NCN. Compositions and methods of use are also disclosed.

In a two-stage process for the biological degradation of complex, non-readily degradable wastewater constituents, acidification takes place in the first stage and anaerobic degradation in the presence of methanogenic organisms in the second stage. In the first stage, the wastewater is treated both with the acidogenic organisms and with dehalogenating and/or desulfonating and/or deaminating strains...

A distribution head having an inlet for accepting a stream of fluid plastic and an outlet for discharging the stream, two pairs of discrete channels in the distribution head extending from the input to the output for splitting the streams into corresponding discrete substreams, selected ones of the channels being of predetermined different lengths to provide lateral mixing of the stream as it pass...

In a method of sterilizing micro-organisms, the micro-organisms are subjected to UV radiation, in a wavelength band which kills micro-organisms, while in an atmosphere of inert gas or of ozone.

A sealing and insulating member (10) for a cylindrical galvanic cell wherein said member comprises a plurality of vent membranes (20) of non-circular configuration separated from thicker sections (22) by stiffening ribs (24). The seal can be readily made from mineral-filled polyolefin material by injection molding.

The grip mechanism (1) is relatively insensitive to dimensional deviations with regard to bottle height and neck dia., and individual bottles can be removed from it with a hand grip without other bottles in a specific group being affected.

The changeover side of the cross-coupling unit has its own connectors (29) and enables user equipment to be changed over to different primary lines by means of loops. The unit has a lowerable front side on the inside (24a) of which are fitted printed circuits (30,31,32). On its side (31a) facing the front surface are secondary connectors in the form of coupling jacks (29) extending from the printe...