An ultrasonic welding tool fabricated of powder metal material includes a body and a welding tip extending axially from the body to a working end. The powder metal material can be ferrous-based and admixed with additives, such as alumina, carbide, ferro-molybdenum, ferro-nickel, chrome or tribaloy. An exposed surface of the welding tip can comprise Fe3O4 oxides. The tool is compacted to the desire...

An apparatus (11) configured to provide positive airway pressure in a respiratory circuit comprises a container (12) configured to be filled to a preselected level with liquids (31); a drop tube assembly(30, 22) comprising a hollow gas tube (30) rotatably mounted in said container having an upper end extending a static distance outwardly of the container and connected to a respiratory circuit down...

A method to activate session control is presented. The method includes receiving a request to activate control of a collaborative session, and determining acceptance of the request to activate control of the collaborative session. The method includes sending an indication, in response to receiving the activation request, the indication indicative of the determined acceptance. The indication in the...

A method to transfer control is presented. The method includes receiving a request to transfer control of a collaborative session from a first user equipment (UE). The method includes sending a request for the transfer of control of the collaborative session in response to the received request to a second UE, and receiving, in response to the sent request to the second UE, an indication of accepta...

A method to transfer control is presented. The method includes sending a message requesting transfer of control of a collaborative session, and receiving notification, in response to the sent message, indicative of a transfer result of said requested transfer of control. The method may include, when the transfer result in the received notification indicates success, relinquishing control of the co...

Wearable disposable absorbent articles such as disposable diapers, having elastically extensible fastening members (also sometimes known as fastening "ears") with particular features, extending from a chassis or main portion of the articles, are disclosed. The fastening members may be highly extensible and have an overall geometry characterized by greater length nearer the chassis or main portion ...

Methods of making or providing ophthalmic lenses include using accommodative error measurements in the design or selection of one or more ophthalmic lenses. In some examples, the ophthalmic lenses are contact lenses.

Processes and methods of recovering desired products from fermentation stillage are presented, including processes and methods of recovering lipids and aqueous materials.

The present invention relates to a method for detecting a viable microorganism in a pharmaceutical composition comprising the steps of providing a filterable pharmaceutical composition; filtering the pharmaceutical composition to provide at least three membranes upon which the pharmaceutical composition is deposited, placing the three membranes onto solid culture media to produce at least three fi...

Described herein are devices, systems and methods for cutting tissue in a patient. In some embodiments, a tissue modification region of a device includes a pair of flexible elongate cutting members extending along the length of the tissue modification region. Each elongate cutting member may be configured to cut a discrete trough into tissue to a depth that is greater than the thickness of the cut...

A flux sharing magnetic circuit has a parallel arrangement of secondary electromagnetic circuits with independent loads. An AC driven primary delivers current to the secondary circuits to maintain charge in their batteries. The batteries deliver DC current to the loads while secondary coils provide battery charging currents to maintain charge in the batteries. When current is not drawn by the batt...

Compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are pharmaceutical compositions comprising the compounds, and methods of using the compounds in the treatment of cancer.

The present disclosure provides a flow meter including a vibrating element configured to be inserted in a measured fluid; a driver circuit to vibrate the vibrating element in its natural frequency of oscillation; one or more additional technology flow meters configured to measure an additional property of the fluid; a data acquisition circuit configured to measure signals effected by the flow of a...

Diseases and conditions associated with tissues of the body, including but not limited to tissues in the eye, can be effectively treated, prevented, inhibited, onset delayed, or regression caused by administering therapeutic agents to those tissues. Described herein are ophthalmic formulations that deliver a variety of therapeutic agents, including but not limited to rapamycin (sirolimus), analogs...

A packaging material with enhanced thermal-insulating performance is disclosed that includes a paper-based substrate and a thermal-insulating layer positioned on at least one surface of the substrate. The thermal-insulating layer contains void structure and is derived from a fluid thermal-insulating composition comprising: 20% to 70% weight of filler; 15% to 70% weight of organic binder; 0.5% to 1...

There are disclosed systems and methods for creating a self-signed implicit certificate. In one embodiment, the self-signed implicit certificate is generated and operated upon using transformations of a nature similar to the transformations used in the ECQV protocol. In such a system, a root CA or other computing device avoids having to generate an explicit self-signed certificate by instead gener...

A non-contact signal propagation property evaluation system for ropes can be deployed for a number of different applications including, but not limited to, moving lines, e.g., crane or winch and static lines, e.g., mooring lines, stays, etc., to evaluate physical properties of the ropes and, in some cases, to help evaluate structural health of the ropes. The system includes a first transducer for ...

Devices and methods for performing extracellular recording of cells, such as excitable cells, cardiomyocytes, and cardiomyocyte precursor cells is provided. An exemplary device includes a nonconductive substrate forming or provided as a base of one or more wells; a recording electrode positioned on the substrate within the well, wherein the recording electrode is accessible to cells when a cell sa...

A system and method for identifying, managing, and synchronizing delivery and storage of promotional material to computing devices associated with a user. The system and method are configured to receive a request from one or more of the user's computing devices to synchronize the delivery of the promotional material to at least a portion of the user's device portfolio. Advantageously, the action t...

The present invention is directed to methods of diagnosing Noonan-like syndrome with loose anagen hair comprising detecting a mutation in SHOC2 gene. One specific diagnostic mutation disclosed is an A-to-G transition at position 4 resulting in a mutation at position 2 of SHOC2 amino acid sequence from serine to glycine. The invention also provides related sequences and kits.