Processes are provided for the syntheses of the human T-antigenic determinant 2-acetamido-2-deoxy-3-O-( beta -D-galactopyranosyl)- alpha -D-galactopyranoside containing an alpha -O-glycosidically linked bridging arm O-(CH2)nCOR. The determinant is coupled to carrier molecules to form artificial T-antigens, and to insoluble supports to form T-immunoadsorbents. The artifical T-antigen is shown to e...

Anthracycline glycosides of the formula (I) I wherein one of R1 and R2 is hydrogen and the other of R1 and R2 is hydroxy, each of R3, R4 and R5 is independently selected from the group consisting of hydrogen and hydroxy and X is hydrogen or trifluoroacetyl, with the provisos that R4 and R5 are not simultaneously hydroxy and that if R3 is hydroxy, then X is hydrogen, which are useful i...

Antitumor anthracycline glycosides of the formula: wherein R1 is hydrogen or hydroxyl and R2 is the .alpha.-L-pyranosyl-hexose II or III II III are prepared from 3',4'-diepi-analogs of daunorubicin and doxorubicin by deamination in a cold acidic medium, such as 1N aqueous acetic and at 0.degree.C with NaNO2. In this series of new anthracyclines showing antileukemic activity against mur...

The anthracycline glycosides I (X = H or OH, R1 = H or CH3, R2 = H or OCH3, R3 = H or OCH3, R2 = R3) and their pharmaceutically acceptable acid addition salts have antitumour properties. They are prepared from 4-demothoxy-daunomycinone or 2,3-dimethyl-4-methoxy-daunomycinone by condensation with an appropriate N-protected hexopyranosyl chloride and removal of the protecting group and, in t...

Reagents useful in the preparation of 5 min -fluorescence-tagged oligonucleotides are disclosed. A class of oligonucleotides is also disclosed.

A printer, preferably a thermal printer, has a line-wide print head with a plurality of closely adjacent print elements. In order to obtain a high-contrast graduation of grey shades of a screen image, the invention provides that the odd and even numbered print elements each comprise a group capable of separate actuation. The two groups can be activated alternately at a separation of one screen lin...

The invention describes a tissue punch according to the subject-matter of German Patent Application P 3630203. In order to permit pulsating aspiration of separated tissue parts from the surgical instruments without any strain on the vacuum storage vessel, a venting solenoid valve is arranged on the tissue collection vessel. The solenoid valve is operated in antiphase to the solenoid valve via whic...

A programming circuit used with a semiconductor memory comprising normal as well as spare memory cells allows any of the normal memory cells to be replaced by a spare memory cell and includes a fuse and a MOSFET connected in series between first and second power supply terminals. A voltage signal at the junction between the fuse and the MOSFET is delivered to the gate of the MOSFET after being del...

The make-up of memory words is controlled by a memory address permutator (32, 50) that permits up to 2! input bit combinations by n address bits. The particular combinations used in any decoder (54, 56) are dependent on the particular application. The new permutator permits scattering of certain faults throughout the usable memory address space while simultaneously accumulating other faults in ...

Plated metal parts, such as sealing lids for semiconductor packages, in which an iron-based alloy layer is electroplated with a first layer of nickel, a first layer of gold is electroplated on the first nickel layer, a second layer of nickel is electroplated onto the first gold layer and a second layer of gold is electroplated onto the second layer of nickel. The resultant plated parts exhibit hig...

Etoposide is produced by reacting a 4 min -halogenoacetyl-4 min -demethylepipodophyllotoxin- beta -D-2,3-di-O-halogenoace tyl-4,6-O-ethylideneglucoside represented by the formula (III): wherein R1 and R2, which may be the same or different, each represent -COCHX2 or -COCX3 wherein X represents a halogen atom, with an alcohol, an amine and/or ammonia to remove the halogenoacetyl groups so...

In a semicondur device comprising a semiconductor element, a pair of electrodes provided on the opposite sides of the semiconductor element, and a cylindrical member provided to surround the semiconductor element and to be in engagement with the pair of electrodes, each of the electrodes has a thread portion on its outer perphery, and the cylindrical member has a thread portion on its inner perihe...

A novel microorganism ATCC-53110 is formed by the protoplast fusion of strains of Streptomyces avermitilis and Streptomyces hygroscopicus. A novel macrolide is isolated from the fermentation broth of this microorganism. The structure of the novel compounds isolated from the microorganism is presented based upon analytical studies. The compounds are highly potent antiparasitic, insecticidal, and an...

Selective esterification of only one of the hydroxy groups in polyols is achieved using an acetalized or a ketalized polyol as the starting material and an enzyme catalysing esterification. Furthermore, the selective esterified polyols may be obtained by concomitant acetalisation or ketalisation and esterification of a ketal or acetal in the presence of an enzyme catalysing esterification.

The present invention relates to novel derivatives of formula I that can be derived from milbemycins, to their preparation and their use for controlling pests, and also to pesticides that contain at least one of these compounds as active ingredient. The novel compounds have the general formula I (I) in which X is one of the groups -CH(OR1)-, -C(O)- or -C(=N-OR)-; R1 is hydrogen or an OH...

This invention relates to a method of producing sucrose fatty acid ester granules by the fluidized bed granulation and drying technique and consists in forming a fluidized bed comprising a sucrose fatty acid ester powder at a temperature not exceeding 60 DEG C., spraying the fluidized bed with an aqueous sucrose fatty acid ester solution having a concentration of 3-20% by weight, as a binder, and...

PURPOSE:To prevent a water stop material from being damaged, when a form is transported, without deteriorating a water stop quality of a tail packing in a shield machine by hermetically sealing a connection part of the adjacent forms by a core material or a water stop material consisting of elastic rubber or the like. CONSTITUTION:An outer form 1 is constituted adhesively mounting a core material ...

A delivery lance for the homogeneous mixing of water-soluble products comprises two coaxial hollow cylindrical members (1), (3) inserted one in the other, the first one (1) being provided with an axial chamber (13) for receiving a mass (66) of soluble product, and the second one (3) defining a surrounding annular chamber (4, 5) which communicates with said chamber (13) through transverse apertures...

The invention relates to an electrode for dielectrically heating thermoplastics. The electrode material or the conducting layer has in this case, compared to normal metal conductors, a relatively high resistance. As a result, the electrode heats itself. In this way, the temperature gradient between workpiece and electrode is reduced and in consequence the heat flow (heat dissipation) in this direc...