A medical device for insertion into a mammalian body, wherein the medical device has a crystalline therapeutic agent thereon. Also provided is a method of delivering a therapeutic agent to a target location within a mammalian body. The method comprises the steps of placing crystals of the therapeutic agent on a medical device, and delivering the medical device to the target location.

The invention involves a submucosa tissue that has the capability of being shape formed or shape configured. The submucosa involves a purified form of submucosa tissue. Optionally, the submucosa can be packaged in such a manner to permit a sterility or maintain sterility of the submucosa.

A medical device (40) including a collagenous biomaterial (10) for causing embolus and treating an aneurysm. The collagenous biomaterial (10) includes a small intestine submucosa (12) that is configured into various components (16) for causing a vascular occlusion or packing aneurysm lumen.

The invention involves a submucosa tissue that has the capability of being shape formed or shape configured. The submucosa involves a purified form of submucosa tissue. Optionally, the submucosa can be packaged in such a manner to permit a sterility or maintain sterility of the submucosa.

A shoe press belt (1) for the shoe press of a paper making machine includes first and second resin layers (2,4) and a base layer (3). Resin is coated and cured on the polished surface of a cylindrical mandrel to form the first resin layer (2) endlessly. An inner layer of the base layer (3A) is formed by spirally winding a relatively narrower belt shaped mesh (31) with warp threads running in the m...

PCT No. PCT/EP92/02163 Sec. 371 Date Mar. 18, 1994 Sec. 102(e) Date Mar. 18, 1994 PCT Filed Sep. 18, 1992 PCT Pub. No. WO93/05728 PCT Pub. Date Apr. 1, 1993.Endoprosthesis with a prosthesis part (4) of viscoelastic synthetic resin such as polyethylene which is intended to be fastened to a support part (1) of more resistant material such as metal by a screw element (3). The screw element has a rele...

The present invention provides for amplification methods for cloning and copying genetic material on surfaces as well as copying biological material insofar as, in a broader sense, it can be classified as a ligand-receptor system. The invention therefore relates in particular to a method for propagating ligands and receptors on at least two surfaces, comprising (a) immobilizing a first ligand on a...

The invention relates to a method for determining the apolipoprotein-E-polymorphism in a human sample by PCR-amplification of a selected base sequence and detection of the apolipoprotein-E-allele, using a multiplex PCR with 6 to 7 different specific primers, four of the primers in each case ending directly at the mutation-specific sites. The primers are characterised inter alia by base mismatches ...

Liquids comprised solely of anions and cations ("ionic liquids") are disclosed as novel components of fluids (and techniques relying upon those fluids) for stimulation of hydrocarbon wells. In particular, the fluids disclosed are useful in matrix acidizing. Formation of the ionic liquids of the present Invention is highly exothermic, hence the heat generated can be used, for instance, to melt de-w...

A power output apparatus (20) of the present invention includes a clutch motor (30), an assist motor (40), and a controller (80) for controlling the clutch motor (30) and the assist motor (40). The clutch motor (30) includes an outer rotor (32) linked with a crankshaft (56) of a gasoline engine (50) and an inner rotor (34) connecting with a drive shaft (22). The assist motor (40) includes a rotor ...

A power output apparatus (20) of the invention includes an engine (50), a clutch motor (30), an assist motor (40), and a controller (80) for controlling the clutch motor (30) and the assist motor (40). In response to an engine stop signal to stop operation of the engine (50), the controller (80) successively lowers a torque command value of the clutch motor (30) and a target engine torque and a ta...

A power transmitting apparatus (20) attached to a crankshaft (56) of an engine (50) includes a clutch motor (30), an assist motor (40), and a controller (80) for controlling the clutch motor (30) and the assist motor (40). When detecting an ignition switch in a starter position, the controller (80) makes a constant current flow through three-phase coils (44) of the assist motor (40) to fix a drive...

Silicone mold release compositions which are a stable blend of hydrophobic-modified organopolysiloxane and an aminoorgano- or mercaptoorgano-functional organopolysiloxane, or a solution in organic solvent of a stable or unstable blend, provide exceptional mold release properties while retaining paintability of molded parts.

The car has a body with a bulkhead (13) which separates the passenger cabin from the engine compartment. A device is arranged in the compartment in order to supply fresh air to the cabin through an opening (17) in the bulkhead, and has an air guide box (23) with an air inlet and outlet (27), a water drain, and an air filter. The guide box is formed by a plastics shell (22) and the bulkhead, and ha...

A chimeric LL2 monoclonal antibody is described in which the complementarity determining regions (CDRs) of the light and heavy chains of the murine LL2 anti-B-lymphoma, anti-leukemia cell monoclonal antibody has been recombinantly joined to the human kappa and IgG1 constant region domains, respectively, which retains the immunospecificity and B-cell lymphoma and leukemia cell internalization capac...

Fusion proteins are described which have a site such as DKTH, DRSH, EKSH or DKSH which is cleavable by copper (II) ions. When expressed in a host cell the fusion proteins provide a cost-effective method for the production of any desired recombinant protein.

Disclosed are methods for producing recombinant cells and especially recombinant mammalian cell lines with enhanced expression of an amino acid sequence. Also disclosed are recombinant mammalian cell lines producing high levels of the amino acid sequence. The methods and recombinant cell lines of the invention have a number of useful applications including use in the efficient and large-scale prod...

The invention provides humanized immunoglobulins that bind to and neutralize gamma-interferon. The antibodies are useful for treatment of diseases of the immune system, particularly autoimmune diseases.

The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of t...

A detachable plug-in pump laser card assembly (14) for placement into an optical fiber amplifier, comprising: a printed circuit board (16), a heat sink (20), a pump laser (18), an optical connector first half plug-in member (22), an electrical connector second half plug-in member (24), and a reel (26) having an optical fiber (28) wrapped therearound. The heat sink is substantially parallel to the ...