A prosthesis for the surgical replacement of a dysfunctional knee joint. The prosthesis includes a tibial platform, one or two tibial bearing inserts, and a femoral component. In a unicompartmental embodiment of the invention, the tibial platform includes a spike for securing the tibial platform to the tibia. The tibial platform, in the unicompartmental embodiment, includes a track, which may be c...

An antibiotic complex designated herein as BBM-1675 complex is produced by fermentation of certain novel strains of Actinomadura verrucosospora. The complex may be separated into two major components, BBM-1675A1 and A2, and four minor components, BBM-1675 A3, A4, B1 and B2, and such components exhibit both antimicrobial activity and antitumor activity.

An apparatus for reading and/or writing an optically readable information structure, arranged in information tracks, on a record carrier, comprises a beam deflection element which is controlled by a control signal obtained from a tracking servo system. The apparatus is provided with a position detection system for detecting the position of the deflection element, and the signal from this detection...

A wire rope which includes a filler material disposed in the interstices between a core rope and respective outer strands and/or in the gaps between individual outer strands wherein the filler element is placed independently in the respective interstices and gaps or an interstice and an outwardly contiguous strand gap as an independent unit. A reinforcing core is anchored in the filler element at ...

There are provided 4'-deoxy-3'- epi-daunorubicin, 4-deoxy-3'-epi- doxorubicin and pharmaceutically acceptable salts thereof of formula where R is H or OH. These have anti-tumour properties. 4'-Deoxy-3'-epi-daunorubicin is prepared from 3'-epi-4'-keto-N-trifluoracetyl- daunorubicin by reduction of the 4'-keto group with sodium borohydride to the corresponding 4'-hydroxy group, reaction o...

23,Demycinosyloxytylosin and its 20-dihydro deriv. of formula (I) (where Q is CHO or CH2-OH, respectively) and their acyl esters, and their acid-addn. salts are new. Streptomyces fradiae NRRl 12171 is new. A culture medium contg. Strep.fradiae NRRL 12171 and assimilable sources of C, N and inorganic salts is new. (I) are antimicrobials esp. effective against Gram-positive bacteria and Mycoplasma s...

A new process for the preparation of 6-deoxyanthracyclinones of general formula I: I wherein R represents a hydrogen atom, a hydroxy group or a lower alkoxy group is described. The process provides a total synthesis of the 6-deoxyanthracyclinones of formula I using 1,2,3,6-tetrahydro-phthalate as starting material. The obtained racemic mixture of the compounds of formula I, if desired, ...

A process for preparing a fructoside, especially a fructosyl disaccharide, comprises reacting a fructosyl saccharide such as sucrose or raffinose with an alcohol or aldose in the presence of a fructosyl-transferase, especially one derived from B. subtilis NCIB 11811, 11872 or 11873. In particular, aldose is a compound of the formula (II) in which A represents a hydrogen atom or the grou...

Chemical demolition is brought about by a water/powder product which is placed in pre-drilled holes, which dry product comprises burnt lime with slaking retarding agents, Portland cement and plasticizer. The expansion of the lime is retarded to such a degree, that at water addition the cement has time to stabilize to a solid body in the entire mixture, placed for example in a predrilled hole befor...

A simple and economic chiral synthesis of optically active methyl L-acosaminide and methyl L-daunosaminide from propenyl acetate, said methyl L-acosaminide and methyl L-daunosaminide being coupling agents for the production of known antitumor agents.

2'-Modified kanamycins, including 2'-deoxykanamycin A, 2'-epikanamycin A and 2'-epikanamycin B, as new compounds are produced starting from kanamycin A by consecutive reaction steps. These new compounds are useful as antibacterial agent.

PURPOSE:To perform the heat bonding of a tape piece to the outer peripheral surface of the opening end part of a metal cylinder without generating a defect by uniformly heating said opening end part while rotating, by a method wherein the opening end part of the metal cylinder is preheated along the circumferential direction thereof and thereafter locally heated in the upstream of a heat bonding p...

PCT No. PCT/JP81/00121 Sec. 371 Date Jan. 6, 1982 Sec. 102(e) Date Jan. 6, 1982 PCT Filed Jun. 1, 1981 PCT Pub. No. WO81/03437 PCT Pub. Date Dec. 10, 1981.In a method for continuously burning particles in a gas or oil heated vertical furnace in which the particles are charged from an uppermost part of the space, and the particles bed fluidized by a burning gas flow is formed in a vertically succes...

A control unit contains a memory in which a program having command words is stored, a condition multiplexer with which it is determined whether a condition indicated in a command word exists, and an address unit in which the actual address of the command word to be targeted in the memory resides. For executing interruptions in the program sequencing at any given moment, a further multiplexer, a fu...

A body implantable intravascular lead with a first layer of plastic defining a tube having a precision lumen therein and at least one electrical conductor wrapped helically along the length of one or more plastic layers. The conductors are substantially parallel along the axis at each end for ease of connection to electrodes and the helical wrap of the conductors may vary throughout the length to ...

According to the invention, for cutting a valve hole and roughening the surrounding surface of an inner tube in a single operation, use is made of a roughening and cutting apparatus having a circular roughening disc (9) which can be lowered onto the flat tube (4) lying in a holder (1) and bears in its centre a downwardly protruding cutting attachment (11) of a height corresponding to the thickness...