PURPOSE:The titled emulsified parenteral solution having improved stability even after long-period storage, containing progesterone, a vegetable oil and lecithin, optionally blended with benzyl benzoate, emulsified and dispersed into such a degree as to make intravenous injection possible. CONSTITUTION:Progesterone that is used as a corpus luteum hormone in a gynecologic field as an injection or t...

PURPOSE:In preparing particles comprising a physiologically active substance, a substance that collapses under acidic conditions with hydrochloric acid, and a substance selected from a monocarboxylic acid, a specific animal or vegetable oil, and wax, to form a protecting film by heat-treating the particles at >= a specified temperature. CONSTITUTION:In preparing particles comprising (A) a physiolo...

A pharmaceutical composition comprising a freely flowable powder, the powder comprising a porous, high absorption silica or silicate having absorbed therein at least 10% by volume of a liquid, pharmaceutically active composition, based on the weight of powder plus liquid, provided that when the liquid pharmaceutically active composition is a corticoid solution the silica or silicate has a mean par...

PURPOSE:The titled dried material obtained by evaporating an aqueous solution containing a proteinic physiologically active substance and a polysaccharide having maltotriose residues as main repeating units to dryness. CONSTITUTION:A water-soluble dried material obtained by evaporating an aqueous solution containing a proteinic physiologically active substance, e.g. lymphokine or proteinic hormone...

1-Cyclopropylquinolone-3-carboxylic acids of the formula in which R1 is hydrogen, methyl, ethyl or beta -hydroxyethyl, and R2 is hydrogen, chlorine or fluorine or salts thereof stimulate the immune system, especially in conjunction with an antigen.

PURPOSE:To obtain an intermediate 2,3-dichloro-1-propanol in high selectivity in preparing the titled compound through chlorination and saponification of allyl alcohol, by using an aqueous solution containing a specific amount of hydrogen chloride as a solvent in the above-mentioned chlorination step. CONSTITUTION:Allyl alcohol is reacted with chlorine in an aqueous solution containing 45-70wt% hy...

NEW MATERIAL:A compound expressed by formula I [R represents H or alkyl; R1 represents alkyl, alkoxyl alkoxy-mono- or di-substituted phenyl, thienyl, OH, etc.) or formula II (R2 represents alkyl, phenyl, etc.) or formula III (R3 represents alkyl, phenyl, etc.: R4 represents alkyl, phenyl etc.)] and its acid-addition salt. USE:Remedies and preventives for hyperpiesis and heart disease such as steno...

The process comprises the reaction of a triterpenyl alcohol with an acid halide of the corresponding organic acid. A pharmaceutical composition for treatment of hyperlipidemia comprising a pharmaceutical carrier and an effective amount of a triterpenyl ester of organic acid other than triterpenyl esters of dibasic saturated fatty acids. A pharmaceutical composition for treating hyperlipidemia whic...