The invention includes liquid formulations of botulinum toxin that are stable to storage in liquid form at standard refrigerator temperatures for at least 1-2 years and to storage at higher temperatures for at least 6 months. The invention also includes methods of treatment using such formulations for various therapeutic and cosmetic purposes.

The present invention is an absorbent structure to be used in absorbent articles, having at least a first region for acquisition/distribution of fluid and a second region for storage of fluid. The first region can contain materials which have a relatively high capillary desorption pressure, as the materials in the second region exhibit a sufficiently high capillary absorption pressure so as to sti...

The invention relates to quinazoline compounds, manifesting antiproliferative activity, particularly antitumor activity, to processes for preparation of such compounds, pharmaceutical compositions containing the said compounds and application thereof for growth inhibition and proliferation of the higher organisms and microorganisms cells, such as bacteria, yeast and fungi. The preferred compounds ...

QUE COMPRENDE: 1) UNA PORCION DE ENTRADA QUE INCLUYE UNA ENTRADA PARA RECIBIR UN FLUIDO EXTRUIBLE Y UN CANAL DE DISTRIBUCION; 2) UNA PORCION DE SALIDA QUE CONTIENE UN PRIMER PICO DE DESCARGA CON UN BORDE QUE DEFINE UNA SALIDA ALARGADA PARA DESCARGAR EL FLUIDO EXTRUIBLE; DONDE, OPUESTO A DICHO PRIMER PICO DE DESCARGA SE UBICA UN SEGUNDO PICO DE DESCARGA QUE TIENE UN SEGUNDO BORDE QUE CON EL PRIMER ...

The invention relates to a method and arrangement for synchronizing a base station in a radio system. In the solution, a synchronization signal is transmitted in a cable for transferring electric power, from which cable the base station filters the synchronization signal and synchronizes its operation according to the synchronization signal.

The genetic material encoding for a specific outer membrane protein (OMP) of Salmonella typhi has been isolated and characterised. This genetic material (ST50) allows for the production of specific proteins/peptides/DNA/RNA for its use in diagnostics, detection of the bacteria S.typhi or in the production of vaccines for typhoid fever.

The invention relates to the use of eletriptan, or a pharmaceutically acceptable salt or composition thereof, for the manufacture of a medicament for the prevention of migraine recurrence and to the use of a 5-HT1B/1D receptor agonist, or a pharmaceutically acceptable salt or composition thereof, for the manufacture of a dual-, sustained-, delayed-, controlled- or pulsed-release pharmaceutical com...

The invention relates to plants for wind-to-mechanical energy conversion and may be used for autonomous production of electric energy. The plant includes a windwheel with arched blades mounted on a vertical shaft of rotation, a housing with wide inlet and narrow outlet, covering the windwheel, the housing outlet is provided with vertical bearing grids and a shaft for winding of flexible screen, ho...

The present invention is concerned with the finding that farnesyl protein transferase inhibitors are useful for preparing a pharmaceutical composition for treating arthropathies such as rheumatoid arthritis, osteoarthritis, juvenile arthritis, and gout.

The present invention relates to therapeutic biaryl derivatives of formula (I), and pharmaceutically acceptable derivatives thereofwherein R1 is a phenyl, naphthyl, pyridyl, thiazolyl, phenoxymethyl, or pyrimidyl group, optionally substituted by one or more substituents selected from the group consisting of halogen, hydroxy, C1-6alkoxy, C1-6alkyl, nitro, cyano, hydroxymethyl, trifluoromethyl, -NR6...

A survey device for use in a borehole formed in an earth formation. The device includes a carrier body carrying earth formation survey apparatus and drilling device arranged at the front end of the device for drilling of the borehole, a device for progressing the carrier body through the borehole in correspondence with progress of drilling by the drilling device and a device for removing the rock ...

The confectionery packaging has a separable film with detachable sections (20) to enclose the article (34). At least rear face of a film section is coated for cold sealing (22) at least partially around the periphery of the film. The larger parts of the sealed zones are superposed after folding to mutually adhere.

A fuel additive for use in the treatment of liquid hydrocarbon fuels to reduce polluting emissions during the combustion of such fuels wherein the additive composition is formulated to contain mineral seal oil, mineral spirits, a glycol alkyl ether and at least one alkyl aromatic ethoxylated surfactant. It has been found that the fuel additive composition of the invention can be blended with such ...

The invention is generally related to processes for the constant emission of volatile products in liquid state which may be either natural or synthetic products or compounds (with or without added solutes); in practice, the process may use solid absorbent masses of different materials of a diverse nature and composition. The invention further proposes the use of specifically designed and mutually ...

The present invention provides an immunogenic liposome composition comprising vesicle-forming lipids and an antigenic construct comprising one or more antigenic determinants and a hydrophobic domain.

The invention relates to a carrier for introduction of a substance into cells, comprising a major capsid protein L1 of human papillomavirus (HPV-L1 protein) which has been intentionally modified to remove type-specific epitope(s) causing production of neutralising antibodies. The invention also includes an oligo- or polynucleotide coding for said carrier, vaccines comprising said carrier or said o...

The invention relates to a carrier for introduction of a substance into cells, comprising a major capsid protein L1 of human papillomavirus (HPV-L1 protein) which has been intentionally modified to remove type-specific epitope(s) causing production of neutralising antibodies. The invention also includes an oligo- or polynucleotide coding for said carrier, vaccines comprising said carrier or said o...

The stand (1) comprises a support frame (4) determining stand height, with a foot plate (2) on top. A fastener device provided on the foot plate can be releasably secured to a shoe (covering).

An antibacterial cleaning composition comprising about 0.05 to about 1 wt. % of a cationic polymer having a charge density of 0.0015 or higher, about 0.2 to about 10 wt. % of an alkylpolyglucoside having a formula: R-O(-G)n wherein R is an alkyl group having from about 8 to about 22 carbon atoms, G is a saccharide residue having 5 or 6 carbon atoms and n is a number from 1-10, about 0.2 to about 5...