A method of ligating two or more molecules, for example, peptides to peptides or peptides to labels is provided. The method may comprise the steps: a) providing a first oligopeptide having a reactive moiety, which is a hydrazine moiety, a hydrazide moiety or an amino-óxy moiety b) providing a second oligopeptide having an activated ester moiety, c)allowing the reactive moiety of the first oligopep...

A device for admitting a cable (1) passing a through-hole (5) in a wall (6) in a manner preventing leakage into the cable or through the through-hole in the wall, wherein the through-hole (5) has an outer portion (5a) of larger diameter, with a seat (4) being formed between the through-hole portions of different diameter, and where the device incorporates a socket (2) of mouldable material, which ...

A sealed removable cartridge adapted for insertion into an assay device and adapted to contain a biologic sample, the cartridge comprising: two or more assay locations adapted to facilitate, within said cartridge, two or more assays of said biologic sample; and an actuator interface adapted to interface with an actuator of said assay device, to transport said biologic sample towards at least one o...

The present invention relates to Hydroxyiminopiperazine Compounds for use and treating or preventing a condition treatable or preventable by inhibiting VR 1 , and compositions comprising an effective amount of Hydroxyiminopiperzine Compound.

This invention relates to compounds and methods for the treatment of cancer. In particular, the invention provides compounds that inhibit Aurora kinase, pharmaceutical compositions comprising the compounds, and methods of using the compounds for the treatment of cancer.

Process for the preparation of 5-(1-piperazinyl)benzofuran-2-carboxamide in which, as intermediate step, 5-bromosalicylaldehyde or one of its derivatives is reacted in a transition metal-catalysed amination with R<2>-piperazine, in which R<2 >is as defined in claim 1.