Generally, a rotary cutting die of the present invention for use in combination with an anvil roll to cut sheet material has a generally cylindrical body extending along a central axis between opposite first and second ends. The body has a Rockwell C scale hardness less than about 50. A cutting blade extends outward from the body to a tip adapted for cutting sheet material passing between the die ...

A strand coating apparatus having an applicator head (40) with a coating material dispenser (10) coupled thereto, a strand guide roller (50) coupled to the applicator head (40) adjacent a coating material orifice of the dispenser (10), the strand guide roller (50) having one or more strand guides each having a corresponding annular groove (52) disposed about a hub, the one or more strand guides di...

A method and apparatus for the cross-hole pressing of cutting inserts (10) i s disclosed whereby a green part (110) is fabricated using metallurgical powde r (260) and an opening (25) is imparted within the green part by placing the metallurgical powder about an oval-shaped core rod (235). Using a press (200 ) with a uni-axial press motion, a core rod is placed within the cavity (210) of a mold an...

A method of manufacturing tires (1) defined by a number of components (3-16), and wherein at least one mobile tire building unit (56) is moved along a feed path (PA, PB) extending through a number of work stations (25-32, 35-40) to receive at least one component at each work station; at least one of the work stations (25-32, 35-40) being a programmable work station, wherein the relative component ...

This invention relates to methods and compositions for the diagnosis of neuroendocrine lung cancers. In particular, the invention concerns the use of cDNA microarrays to facilitate the differential diagnosis of neuroendocrine tumor types.; L'invention concerne des procédés et des compositions utiles dans le diagnostic de cancers du poumon neuroendocriniens. Elle concerne en particulier l'utilisati...

In one aspect, the invention is directed to polypeptides having an amylase activity, polynucleotides encoding the polypeptides, and methods for making and using these polynucleotides and polypeptides. The polypeptides of the invention can be used as amylases to catalyze the hydrolysis of starch into sugars.; Dans un aspect, La présente invention concerne des polypeptides possédant une activité amy...

Methods and kits are provided for predicting the response of patients with B-cell chronic lymphocytic leukemia (CLL) to treatment with agents that bind to the CD20 and CD 52 antigens on the surface of B lymphocytes. The methods of the present invention are for identifying patients who are refractory and patients who are responsive to therapy with such agents by analyzing the genome of cells obtain...

A method of determining a suitable chemotherapeutic agent for an individual comprises the steps of assaying a biological sample from the individual for BRCA1 activity. When the activity is greater than or equal to a normal level, an antimicrotubule chemotherapeutic agent is recommended. When the activity is below a normal level, a DNA damaging chemotherapeutic agent is recommended. BRCA1 activity ...

Die vorliegende Erfindung betrifft spezifische Konstellationen der genetischen Variabilität des MDR1 Gens, ausgedrückt in Form von Haplotyppaaren, und deren Verwendung zur individuellen Arzneimitteltherapie und zur Risikovorhersage von Tumorerkrankungen beim Menschen. Die vorliegende Erfindung betrifft ausserdem die Identifizierung von weiteren funktionell relevanten Haplotypen des Gens MDR1.; The...

An illumination box (1) for true, reproducible colour reproduction of an object, comprising side walls (2), a top plate (3) and a bottom plate (4), wherein between the top plate (3) and the bottom plate (4) there is provided a light diaphragm (5) which divides the illumination box (1) into a light chamber (L) above the light diaphragm (5) and an object chamber (O) beneath the light diaphragm (5). ...

A navigational control system (10) for altering movement activity of a robotic device (100) operating in a defined working area, comprising a transmitting subsystem integrated in combination with the robotic device (100), the transmitting subsystem comprising means for emitting a number of directed beams, each directed beam having a predetermined emission pattern, and a receiving subsystem functio...

Polymeric foam composites (PFCs) containing a polyurethane or polyisocyanurate foam can pass both ceiling and wall portions of the United Building Code 26-3 Room Corner Burn Test and can meet requirements for Factory Mutual 4880 approval. Polymeric foam composites of the present invention have a front face with an exposed metal sheet. Polymeric foams in the PFCs contain at least 4 weight-percent h...

Microcellular polyurethane flexible foams suitable for use as lightweight shoe sole components are produced by dissolving carbon dioxide into one or both of the iso-side or resin-side of an isocyanate-prepolymer-based microcellular polyurethane foam formulation. The resultant foams possess more uniform cell structure and enhanced physical properties as compared to all water-blown foams of the same...

The invention relates to a method finding holes, and other related defects a nd measuring cheracteristics of sheets of industrial material. Optical detectio ns systems are constantly plagued by intense ambient light and challenged in accurancy. The invetion exhibits a defect detection method and means that is resistant to intense ambient light and is capable of inspecting sheets of metareial (410,...

A process and device for storing and accessing data in databases of a computerized travel reservation system. According to the invention: for each type of information to be stored, there are created rules associating: a set of criteria defining the trips to which the information applies, a content representing the value of the information to be applied; the set of criteria of a rule includes a pai...

A process for managing commercial transactions comprising: receiving a first message from a merchant, said first message defining the amount of a card holder's transaction in a first currency defined by the card, receiving or generating a second message defining the amount of the card holder's transaction in a second currency determined by the merchant, sending (212) a request for payment of the t...

A method and system for managing risk for contracts offered for trading in systems is disclosed. A complete set of contracts includes the contracts, each of which matures upon events) occurring. The complete set guarantees at least an initial settlement value at at least one particular time. The complete set also corresponds to a settlement value, which is based upon the initial settlement value a...

A method and system for improving liquidity of transactions for a plurality of contracts is disclosed. In one aspect, the method and system include providing a special purpose vehicle for buying and/or selling at least a portion of a complete set including the plurality of contracts. The complete set guarantees at least an initial settlement at at least one particular time. The complete set also c...

A method and system for improving liquidity of transactions for a first plurality of contracts for a pari-mutuel (PM) pool or auction is disclosed. In one aspect, the method and system include providing a complete set including a second plurality of contracts. The complete set guarantees at least an initial settlement value at at least one particular time. The complete set also corresponds to a se...

Methods and systems enabling an interactive electronic commerce system that facilitates dissemination and management tasks associated with advertisements and other advertising, promotion or information interchange messages, such as coupon offers and sales announcements. In one embodiment, the present invention further provides advertisers the ability to assess the correlation between the broadcast...