A process for production of a borohydride compound. The process comprises the steps of (a) combining a boron-containing salt, at least one of a metal and its hydride; wherein the metal is Be, Mg, Ca, Sr, Ba, Al, Ga, Si or a transition metal; and a solvent in which the borohydride compound is soluble; (b) grinding a mixture formed in step (a) to form the borohydride compound; and (c) separating a s...

Titanium dioxide having a ratio D_top/D₅₀ of 1 to 3, between the maximum particle diameter D_top and the average particle diameter D₅₀, as determined based on observing the primary particles by a field emission-type scanning electron microscope. A production process of the titanium dioxide comprises performing a vapor phase process of reacting a titanium t...

A core insert for a glass molding machine includes a substrate and a protective film. The substrate is made of ceramic, such as tungsten carbide (WC), carborundum (SiC), silicon nitride (Si₃N₄), or boron nitride carbide (BNC). The protective film is deposited on a surface of the substrate, and the protective film is made of a fullerene (C₆₀ or C₇₀). The ...

A binder is mixed to alumina powder with a purity of 99.5% or more (step S11), the mixture is granulated (step S12), resultant granule powder is formed with a die (step S13), and a formed compact is sintered in a hot-pressing manner (step S14).

A dielectric ceramic comprising as a main component (Ba,Ca)(Ti,X)O

The invention is to provide a catalyst for long-term, high-yield and stable production of ethylene and propylene in an efficient and simple method of catalytic conversion from a hydrocarbon material. The invention relates to a method for producing ethylene and propylene by contacting a hydrocarbon material that contains an olefin having from 4 to 12 carbon atoms in an amount of at least 20 % by we...

The invention relates to a process by which C₄- to C₆-olefins or an essentially sulfur-free olefin cut comprising C₄- to C₆-olefins is isomerized over a catalyst comprising an element of the eighth transition group of the Periodic Table, in the presence of at least one added sulfur compound, and any polyunsaturated hydrocarbons contained therein are sele...

The present invention provides a process for the production of an alkenyl carboxylate by reacting an alkene, a carboxylic acid and a molecular oxygen-containing gas in a reaction zone in the presence of a catalyst at an elevated reaction temperature, T, to produce an outlet stream from the reaction zone comprising alkenyl carboxylate and oxygen, and wherein in said process the catalyst is contacte...

The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

The invention includes a combination of a compound of formula I as phosphatidylinositol 3-kinase inhibitor with an anti-inflammatory, bronchodilatory or antihistamine drug substance, said agent of the invention and said drug substance being in the same or different pharmaceutical composition.

This invention relates to a novel salt form of dopamine agonist 5-[(2R,5S)-5-methyl-4-propylmorpholin-2-yl]pyridin-2-amine (I): More particularly, this invention relates to 5-[(2R,5S)-5-methyl-4-propylmorpholin-2-yl]pyridin-2-amine di-(1S)-camphorsulfonate (di-S-camsylate) and to processes for the preparation of, intermediates used in the preparation of, compositions containing, and the uses of th...

The present invention is directed to compounds of Formula I: and Formula II: (where variables R 1 , R 2 , R 3 , R 4 , A, B, G, J, Q, T, U, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceut...

The present invention provides a process for the manufacture of the compound of formula (1): which is a key intermediate in the manufacture of camptothecin (CPT). This compound continues to serve as an attractive and promising lead structure for the development of new anti-cancer drugs.

The present invention provides soluble CTLA4 mutant molecules which bind with greater avidity to the CD80 and/or CD86 antigen than wild type CTLA4 or non-mutated CTLA4Ig. The soluble CTLA4 molecules have a first amino acid sequence comprising the extracellular domain of CTLA4, where certain amino acid residues within the S25-R33 region and M97-G107 region are mutated. The mutant molecules of the i...

The present invention relates to a block copolymer (A) including a (meth)acrylic polymer block (a) and an acrylic polymer block (b). The (meth)acrylic polymer block (a) is preferably copolymerized with a monomer having a functional group having high cohesive force, such as a carboxyl group, so that the 5%-weight-loss temperature is 300 DEG C or more or the tensile strength is 3 MPa or more, and th...

An unsaturated multibranched compound (A-1) capable of being speedily cured by irradiation with actinic radiation, which is prepared by reacting (a) a compound having two or more oxetane rings in the molecule with (b) a compound having in the molecule two or more carboxyl groups (with the proviso that when the compound (a) has two oxetane rings, the compound (b) has three or more carboxyl groups) ...