The present invention relates to highly diastereoselective processes for production of cis-nucleosides and nucleoside analogues and derivatives in high optical purity and intermediates useful in those processes.

The present invention relates to highly diastereoselective processes for production of cis-nucleosides and nucleoside analogues and derivatives in high optical purity and intermediates useful in those processes.

A method is provided for the preparation of a sucrose 6-ester by: (i) reacting sucrose with a trialkyl orthoester or with a ketene acetal in an inert organic solvent in the presence of an acid catalyst to provide a sucrose alkyl 4,6-orthoester, (ii) treating tho sucrose alkyl 4,6-orthoester under mild aqueous acidic conditions to provide a mixture of sucrose 4- and 6-monoesters, (iii) treating the...

A remotely retunable receiver for use in a satellite video programming distribution system includes the capability to retune groups of subscribers to different satellite feeds during a blackout of a video programming event. To achieve flexible control over program blackouts, a receiver retune command message is selectively sent to desired groups of descramblers at CATV satellite downlinks. The ret...

2103378 9220822 PCTABS00017 Therapeutic oligonucleotide analogs which have nuclease resistance and improved cellular uptake are provided. Replacement of posphorodiester inter-sugar linkages found in wild type oligomers with four atom linking groups forms unique di- and polynucleosides and nucleotides useful in regulating RNA expression and in therapeutics. Methods of synthesis and use are also dis...

2103464 9220823 PCTABS00017 Therapeutic oligonucleotide analogs which have improved nuclease resistance and improved cellular uptake are provided. Replacement of phosphorodiester inter-sugar linkages found in wild type oligomers with four atom linking groups forms unique di- and poly-nucleosides and nucleotides useful in regulating RNA expression and in therapeutics. Methods of synthesis and use a...

An arrangement for welding foil webs includes two coacting cog wheels (10, 11), between which the foil webs are advanced, and a heat source. The heat source is comprised of a heating wire (21) which is placed in the close proximity of the coacting parts of the cog wheels and the ends (211, 212) of which are connected to a current source (23) which functions to heat the wire (21) to a temperature a...

An arrangement for welding foil webs includes two coacting cog wheels (10, 11), between which the foil webs are advanced, and a heat source. The heat source is comprised of a heating wire (21) which is placed in the close proximity of the coacting parts of the cog wheels and the ends (211, 212) of which are connected to a current source (23) which functions to heat the wire (21) to a temperature a...

An arrangement for enveloping an object located between two heat weldable webs (11, 13) of enveloping material includes two coacting welding jaws (14, 18; 15) for joining the webs together in their transversal direction on mutually opposite sides of the object. The welding jaws extend in the transverse direction of the webs, across the whole width thereof. One of the jaws is a wire-carrying jaw (1...

2102925 9220843 PCTABS00017 A nozzle assembly for forming hollow fibers, particularly a "Z-fiber" having longitudinally oriented trabeculae with the fiber wall, is disclosed. The nozzle assembly (10) contains a replaceable nozzle cap (28), a replaceable seal-guide (26), and a retractable central bore (14) used to supply core material for the hollow fibers. The Z-fibers are particularly useful in e...

A warming and cooling system includes a cooling device for installation in an upper part of a living space, a warming device for installation in a lower part of the living space, a heat pump having an evaporation portion and a condensation portion and serving as a heat transfer drive source for transferring heat recovered from the cooling device, a heat exchanger to which the recovered heat is tra...

An expansion and contraction type guard baton causing less rattling or deviation even after repeating use and free from the worry of slipping off by the force of thrusting and extending the baton main body even if the wall thickness is decreased to reduced the weight. A plurality of cylindrical members are combined in a telescopic manner in which the conically inclined surface at the top end of an...

To ensure desirable spinning conditions in a ring spinning apparatus, the apparatus is provided adjacent to the guide ring (5), on which a traveler (4) is mounted, with a track (10), which surrounds the axis of the spindle (1) and serves to deflect the yarn (3) approaching the traveler (4) so that adjacent to the traveler (4) the yarn portion moving from the deflecting track (10) to the traveler (...

A shell for a chair in which a bottom shell structure and a backrest shell structure are connected to supporting frame members. The bottom shell structure has a bottom portion and a partial backrest portion that are connected by a curved portion with plural slots. Sideways notches are connected to the extreme left and right slots and extend toward the left and right edges of the shell structure. T...

The invention relates to a method and an arrangement for selective driving of valves of small drive power by means of light. A control generates control signals which are modulated onto a light source which emits said control signals which are received by all the valves via solar cells. However only the addressed valve is switched. No cabling is necessary between the control and the valves.

A yarn feeding device which can be switched between positive feed and intermittent feed comprises a yarn guide element (31) associated with the lower edge (30) of a storage drum (3) and which can be displaced by means of an electromagnetic setting member (32) selectively to a first position (solid lines) allowing the intermittent feed and a second position (broken lines) producing the positive fee...

The invention is used in an actuating drive comprising two friction partners, in particular a geared actuating drive with a toothed worm wheel which braces itself radially with a cup-shaped edge part against an outer rim part of a concentric slave disc which is driven over an at least tangentially elastic damping liner. The invention is designed to prevent squeaking noises between the friction par...

The method, which is based on a process for the desalination of seawater, makes it possible to obtain the following main products: H2O, NaCl, KCl, NaNO3, KNO3, Hg2Cl2, Mg(OH)2, Ca(OH)2, Na2B4O7, KOCl4, BaSO4. It is substantially a distillation process at a thermodynamically optimum temperature. This has been made possible as a result of original pre-treatment of the seawater based among other thin...