Für eine Hüftgelenk-Endoprothese mit einem einstellbaren Prothesenkopf, der mit einem im Oberschenkelknochen festsetzbaren Stiel verbunden ist, wird vorgeschlagen, Überlasten, die zu einer Beschädigung des in den Oberschenkelknochen implantierten Prothesenteiles und damit auch zu einer erneuten Implantation führen würden, in einem Begrenzungselement aufzufangen. Das Begrenzungselement ist im Proth...

An endoprosthesis (16) for partly or completely replacing the humerus, comprising a head portion (14) which is connected to an elongate shaft portion, wherein the spherically formed head (32) includes openings (36) for fixing a number of bands, whereby the head (32) includes an at least partly circumferentally extending groove (34) distally below its largest diameter to receive a band (38) made of...

A mechanism for handling processing errors in a computer system. The mechanism includes a first means for processing a stream of instructions, second means for detecting an error caused by a timing dependant defect and occurring during processing of the instruction by the first means and third means for varying the instruction processing cycle time of the first means in response to the detection o...

The invention relates to a reusable dispensing package (10) for dispensing medication in the form of tablets, pills, capsules or the like in a predetermined sequence, said package (10) comprising a reusable container (11) having a cover (12) and a base portion (13), the cover (12) being engageable with the base (13) to form the container; the base portion (13) being adapted to receive a blister pa...

A collection container for body fluids includes a bag (16) having walls (68,70) constrained for movement with relatively stiff and flexible sheet members (78,80). A squeezing force applied to the side edges (85,87) of the members causes them to bend outwardly thereby expanding the bag (16). A holder (18) is provided to maintain the bag (16) in the expanded condition. The bag (16) is intended for c...

This invention relates to certain novel 2 min -halomethylidene, 2 min -ethenylidene and 2 min -ethynyl cytidine, uridine and guanosine derivatives, and compositions thereof, which are useful in the treatment of patients afflicted with neoplastic or viral disease states.

In the encoder an audio input signal is firstly given an adaptive pre-emphasis characteristic by a pre-processing circuit (16) and is then converted to a digital signal for transmission by a delta-modulator (22). In order to minimise the digital bit rate the delta-modulator (22) is rendered adaptive by deriving a step-size control signal in a circuit (18) responsive to the slope of the input signa...

The compliance assembly comprises a plurality of circumferentially spaced compliance mechanisms 7 each comprising a lever arm 12 pivotable about point along its length, a support leg 3 connected between an end of the lever arm 12 and a point on the tool holder assembly (2, fig 1 not shown). The lever arm 12 is biassed towards a horizontal attitude by springs 14, 15. The compliance of the assembly ...

Amphotericin B salt forming compsn. comprises amphotericin B of formula (I) and a salt forming acid in a soln of MeOH, DMF and CH2Cl2, in an amt to enhance the crystallintiy and purity of (I), and water. Also claimed is a process for the purification and crystallisation of (I) which comprises: (a) forming a soln. of (I) in MeOH, DMF, and acid capable of forming a salt with (I); (b) sepg. (I) extra...

Homoconjugated antibodies with high avidity for antigen have increased therapeutic activies and are utilized in pharmaceutical and diagnostic compositions. The homoconjugates, typically prepared from monoclonal antibodies of the IgG class which bind to the same antigenic determinant, are covalently linked by synthetic cross-linking. The homoconjugates are comprised of at least two immunoglobulin m...

Oligonucleotides having a low molecular weight tail molecules joined to the 3' terminus of the oligonucleotide via a linking molecule of structure (I) or (II) wherein Z is (III), (IV), (V), (VI) or (VII), m and m' are positive integers less than 11, n is 0 or 1 and Q is a connecting group, are synthesized by selectively reacting three independent functional groups on the linking molecule, i.e., an...

A method for preparing partially acylated carbohydrate derivatives, particularly saccharose acetate, by reacting the initial carbohydrate with an acylating agent, wherein the method is carried out in a reaction medium consisting of an organic phase and an aqueous phase. Selecting the organic phase allows the average degree of substitution of the desired partially acylated carbohydrate derivative t...

The time required for the program verify and erase verify operations can be shortened. The change of threshold values of memory cells can be suppressed even if the write and erase operations are executed repetitively. After the program and erase operations, whether the operations were properly executed can be judged simultaneously for all bit lines (BL) basing upon a change, after the pre-charge, ...

An integrated circuit memory having redundant rows, for replacing a row in a primary array having a defective memory cell, is disclosed. For each primary row that is to be replaced, a fuse is opened between the output of the row decoder and the word line for the replaced row. A power-on reset circuit is provided in the memory for determining if the power supply voltage has reached an adequate volt...

New functional ganglioside derivatives comprising ester, amide and peracylated derivatives of gangliosides, preparation procedures therefor, pharmaceutical preparations containing the same, and the therapeutic use of the derivatives.

The invention discloses new oligodeoxyribonucleotides of animal origin, having a molecular weight comprised between 4OOO and 1OOOO daltons, that can be obtained by fractionation of polydeoxyribonucleotides or otherwise by chemical or enzymatic depolymerization of high molecular weight deoxyribonucleic acids. The new compounds are endowed with a significant anti-ischemic activity.

New A83543 components and salts thereof, and N-demethyl derivatives are useful for the control of insects and mites. Methods for making the new A83543 components by culture of Saccharopolyspora spinosa NRRL 18719, NRRL 18720, NRRL 18723 are provided. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided. Pseudoaglycones of Aare useful for the preparatio...

La presente invención se refiere a un metodo para producir una película de barrera al oxígeno que consiste de: a) coextruir una película de capas múltiples que consiste de una capa exterior de copolímero de etileno y alcohol de vinilo y por lo menos una capa ligada la capa exterior y que consiste de un material polimerico que se selecciona del grupo que consiste de una poliolefina o una poliolefin...

A golf club and methods of assembling and disassembling the shaft and head. The golf club includes a shaft and a head affixed to one another by having a male portion embedded in a female portion, or embedding hole, the two being made of a composite material or plastic, and a heat-conductive intermediate ring is located between the internal peripheral surface of the female portion and the external ...

A welding seal assembly for use in joining and sealing two telescoped tubular elements in a lap joint, specifically a tubular pipe in a pipe socket formed in a pipe fitting. The seal assembly comprises a thermoplastic welding sleeve with an embedded electric heating coil for fitting between the pipe and the socket; a mounting collar including a ring-like body that is fitted over the pipe and again...