Se describen tabletas que comprenden formulaciones estables hidroliticamente de sal disodica de (6-(5-fluor-2-(2,4-5trimetoxifenilamino) pirimidin-4-ilamino)-2,2-dimetil-3-oxo-2h-pirido.; Disclosed are tablets comprising hydrolytically stable formulations of (6-(5-fluoro-2-(3,4,5-trimethoxyphenylamino) pyrimidin-4-ylamino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl phosphate di...

Los derivados de y-lactna del acido 15a, 16a-metilen-17-hidroxi-19-nor-17-pregna-4-en-3-ona-21-carboxilico de la presente invencion poseen efectividad gestagenica.

La invencion se refiere a derivados de 15,16-metilen-17-(1'-propenil)-17-3'-oxidoestra-4-en-3-ona que tienen la formula quimica general I, donde Z, R4, R6a, R6b, R7 y R18 tienen los significados indicados en la reinvindicacion 1 y sus solvatos, hidratos y sales.; The invention relates to 15,16-methylene-17-(1′-propenyl)-17-3′-oxidoestra-4-en-3-one derivatives with the general chemical formula I, w...

La invencion se refiere a derivados de y-lactona del esteroide del acido 17-hidroxi-19-nor-21-carboxilico de la formula quimica I, donde R4, R6a, R6b, R7, R15, R16a, R16b, R18 y Z tienen los significados indicados en la reinvindicacion 1, asi como sus solvatos, hidratos, estereoisomeros y sales.; The invention relates to 17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the c...

El Ócido 4-(4-(2-adamantilcarbamoil)-5-tert-butilpirazol-l-il)benzoico y sales farmaceuticamente aceptables de este y una fora cristalina particular del agente.; 4-[4-(2-Adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid and pharmaceutically-acceptable salts thereof and a particular crystalline form of the Agent (Form 1); their use in the inhibition of 11βHSD1, processes for making them an...

La invencion proporciona ciertos nuevos derivados de 6-heteroaril-5-metil-3-oxo-4-(3-(trifluorometil)fenil)-3-4-dihidropirazina-2-carboxamida y sales farcamaceuticamente aceptables de los mismos y formas particulares de los mismos.; The invention provides certain novel 6-heteroaryl-5-methyl-3-oxo-4-[3(trifluoromethyl)phenyl]-3,4-dihydropyrazine-2-carboxamide derivatives and pharmaceutically accept...

La invencion proporciona formulaciones de polvo seco que comprenden un derivado del acido ascorbico que presenta un comportamiento inhalatorio bueno e inhaladores de polvo seco que las contienen.; The invention provides dry powder pharmaceutical formulations comprising an ascorbic acid derivative that demonstrate good inhalation performance and dry powder inhalers containing them.

Compounds, methods, uses, compositions, kits and packages for the prevention and/or treatment of neural injury or a neurodegenerative disease, based on the use of a retinoic acid derivative, such as fenretinide, and/or analogs, derivatives, prodrugs, precursors thereof, and/or salts thereof, are described.

A transmitter generates MUX-PDUs for video, audio, data, and/or control streams based on a fixed PHY packet size such that all or a substantial percentage of the MUX-PDUs conform to the PHY packet size. The MUX-PDUs have variable sizes and are mapped to PHY packets such that (1) each MUX-PDU that is smaller than the PHY packet size is sent in one PHY packet and (2) each MUX-PDU that is larger than...

Razor handles are provided. In one aspect, a razor handle includes a housing constructed to hold a battery, an aperture in the housing, a microporous membrane covering the aperture and sealed against a surface of the housing surrounding the aperture, a cover disposed over the membrane and aperture, and a space provided between the cover and the surface of the housing, the space being configured to...

A method and apparatus for an iterative cryptographic block under the control of a CPU and without a fixed number of stages. In one embodiment, a first cryptographic block descrambles received information using an internal key or a preprogrammed key to form a descrambled key or descrambled data. A data feedback path stores the descrambled data as internal data and provides the internal data or the...

A fuel cell system includes a fuel cell body that generates electricity through electrochemical reaction of a first reactive gas and a second reactive gas, a first gas supply passage and a second gas supply passage supplying the first reactive gas and the second reactive gas to the fuel cell body, a first gas discharge passage and a second gas discharge passage discharging an off-gas of the first ...

The invention encompasses stable candesartan cilexetil of fine particle size, wherein desethyl-candesartan (desethyl-CNS) within the stable candesartan cilexetil does not increase to more than about 0.1%w/w by HPLC relative to the initial amount of candesartan cilexetil, when the stable candesartan cilexetil is maintained at a temperature of about 55°C for at least 2 weeks, methods of making the s...

High efficiency and low noise is achieved in an automotive engine-cooling fan assembly by flaring the inlet to the shroud barrel, and shaping the tips of the fan blades to conform to the shape of the inlet. Separation of the flow entering the fan is reduced by extending the flare over the axial extent of the blade tip, and tip clearance losses are reduced by controlling recirculation along the ent...

A disc copying or recording device and a disc label printer are mounted in a common assembly, and include a printhead moveable along a guide shaft on a frame. A disc transport carriage is mounted on the same guide shaft as the printhead, can be moved along this guide shaft for picking up discs in a storage area, moving a disc to a tray or support used for recording and then to a disc tray or suppo...

A disclosed electrophoretic fluid includes a solvent; and first, second, and third dispersible particles having different optical properties and dispersed in the solvent, the first dispersible particles being uncharged, the second dispersible particles being positively-charged electrophoretic particles, and the third dispersible particles being negatively-charged electrophoretic particles.

A boost converter boosts a DC voltage of a DC power supply. An inverter converts the output voltage of the boost converter into an AC voltage. A control device that controls the boost converter reduces an output voltage instruction value of the boost converter when the rotation speed of the AC motor decreases and an absolute value of a variation rate of the rotation speed is not less than a predet...

An exhaust gas analysis method comprises applying a laser beam to the exhaust gas discharged from an internal combustion engine, receiving the laser beam that has passed through the exhaust gas, and measuring the concentration of any of the components contained in the exhaust gas based on the received laser beam. The exhaust gas analysis method further comprises detecting the absorption spectrum o...

An object of the present invention is to provide an electric double layer capacitor carbon material and an electric double layer capacitor which can exhibit excellent charge/discharge characteristics. The carbon material for electric double layer capacitors in accordance with the present invention is characterized in having the BET specific surface area in a range of 300 - 1000 m 2 /g, the carbo...

An automatic gas discharging device for lithium-bromid machine and a method thereof comprises an automatic gas extraction unit, a gas extraction chamber, a gas-liquid separation chamber and a gas-storing chamber. A valve F1 is provided in the outlet of a solution pump of the lithium-bromid machine. A gas-discharging and liquid-receiving tube, together with a valve F2, is provided between the pump ...