The invention relates to N-glycosylated carboxamide derivatives of Formula I which are useful for influencing the body's inherent defenses, e.g. for increasing immune system antibodies. Also included in the invention are compositions containing said N-glycosylated carboxamide derivative of Formula I as active ingredients and methods for the use of said compounds and compositions.

As new semi-synthetic antibiotic derivative are provided N-methanesulfonic acid derivatives of istamycin A or B which are lower toxic than the parent antibiotic and retain usefully high antibacterial activity. They are produced by N-sulfomethylation in such way that istamycin A or B is reacted with an aldehyde such as paraformaldehyde and sulfurous acid or sulfite reagent.

Compounds of the general formula (I) (I) (wherein X represents a halogen atom; R1 and R2 respectively represent a combination selected from the group consisting of: a hydroxy group and a hydrogen atom; a halogen atom and a hydrogen atom; and a hydrogen atom and a halogen atom; and R3 and R4, which may be the same or different, each represent a substituent selected from the group consist...

A belt-mountable scabbard for carrying a sportsman's knife comprises spaced apart walls defining an elongated recess for receiving and protecting the blade of a knife carried in the scabbard. A knife blade sharpener is permanently mounted on the scabbard and comprises a blade-receiving sharpening slot formed in the scabbard and a pair of angularly arranged abrasive elements permanently attached to...

Published without abstract.

Starting from the known 4'-deoxy-4'-iodo-N-trifluoroacetyldaunorubicin, two new anthracycline glycosidic antibiotics, the 4'-deoxy-4'-iodo-daunorubicin and 4'-deoxy-4'-iodo-doxorubicin, have been prepared by known procedures. Both the new glycosides have been found to be endowed with outstanding antitumoral activity.

A new acidic polycyclic ether antibiotic has the formula: +TR and can be prepared by the submerged aerobic propagation in aqueous nutrient media of Streptomyces halstedii ATCC 31812. The antibiotic and its cationic salts are active against a variety of microorganisms and are effective in controlling coccidiosis, enteritis, swine dysentery and theileriosis as well as being effecti...

The invention relates to the treatment and prevention of cancerous conditions by the administration of a composition including the compound of the formula: (1) or of an aqueous, alcoholic or aqueous alcoholic or other extracts of plants of the Hypoxidaceae family and particularly the plants of the genus Hypoxis and the genus Spiloxene.

PURPOSE:To improve the bonding force of a molded plastic article with a modified polyolefin, by metallizing the surface of the molded plastic article with Al, Sn (oxide), etc., and fusing a carboxyl-containing modified polyolefin to the metallized surface. CONSTITUTION:The surface of a molded plastic article (excluding a sheet) made of polyester, nylon, polyolefin, polycarbonate, polystyrene or ac...

1. A multipole electrode arrangement for stimulating body tissues comprising at least two spirally wound metallic conductors which are insulated from one another, where the individual conductors (2, 3 ; 11, 12) consist of a metal tape which is at least partially surrounded with insulating material (4, 5 ; 13) and the insulating material (4, 5 ; 13) serves as a carrier for the metal tapes (2, 3 ; 1...

1. A multi-polar coaxial electrode lead (1) for an implantable heart pacemaker, comprising coaxially arranged, electrical conductor coils (2, 5) which are each separated from one another by at least one insulating layer (4) and comprising a central opening (3) for a guide wire, wherein the innermost conductor coil (2) comprises wire, characterised in that the conductor coil(s) (5) applied to this ...

Process for open and closed loop control of the melting and bonding process during the jointing (welding, riveting, embedding, flanging, tamping) of mouldings of reinforced or unreinforced thermoplastics as well as during the embedding process of components of a non-thermoplastic nature in reinforced or unreinforced thermoplastic materials by means of ultrasonic energy, in which the electrical pow...

The feeder comprises a rotary hollow arm (5) through which the material is wound as turns onto a supporting body (7, 9) comprising a plurality of rigid guides (9) each of which has a ring shape and a C-cross- section open to the ring outside. The guides accommodate balls (10) (or rollers) in contact with one another and outwardly projecting. Said body is mounted on bearings carried by the shaft (4...

This invention relates to an energy-efficient process for dewaxing hydrocrackate and manufacturing a stabilized and dewaxed hydrocracked lubricating oil stock from hydrocarbon feedstock boiling above about 343 DEG C.

In an apparatus for stuffing flowable product into a shirred tubing disposed on a stuffing horn to produce stuffed tubular articles of predesired length on a continuous basis, a sensing member is employed for detecting movement of the trailing end portion of the shirred tubing on the stuffing horn which activates control for interrupting the stuffing operation of the apparatus so as to terminate t...

The method entails a defined area of skin being contacted with the coated side of a support coated with adsorbents, e.g. a glass plate coated with silica, and the sebaceous substances adsorbed by the coating being visualised by decomposition or the action of reagents and quantified by photography or photometry, and is easy to carry out but accurate and very reproducible for all sebaceous component...

Process for fractionation of compounds, which in essentially non-polar solvents form mixed or co-micelles, and hence cannot normally be fractionated by membrane filtration. By dissolving a mixture of such compounds in a solvent system in which selective micelles formation occurs, and contacting the solution under pressure with a semi-permeable membrane to separate the mixture into a permeate and a...

IMPROVEMENTS IN OR RELATING TO DIELECTRIC OPTICAL WAVEGUIDES A method of coating a fibre in which a sleeve of polymer is extruded, fibre is fed into the sleeve as it is formed, and the diameter of the sleeve is reduced by a drawing process to produce a sleeve of polymer which loosely envelops the fibre. We also provide a fibre having a tubular sleeve of polymer, the sleeve having its molecules ori...

In order to make a sound-proofing lining comprising a mat of foamed material more easy to work, the mat of foamed material is applied to a stiff, deformable support which makes the mat easier to handle and easier to fix.

The soundproofing elements consist of a concrete-like, bulk-porous, sound-transmitting, wire mat-reinforced layer and of a porous sound-absorbing layer, e.g. a mineral fibre board, and of a sound-insulating layer made of impervious building material, e.g. asbestos cement, which is applied thereto. The layer of asbestos cement can be replaced by a concrete-like, bulk-porous layer. For stabilisation...