L'ensemble prothétique d'articulation de l'épaule comprenant un élément glénoïdien sous forme d'une tête d'articulation (1) convexe du type hémisphérique présentant des agencements de fixation au niveau de la glène de l'omoplate, ladite tête coopérant avec une surface d'appui et de glissement (2) que présente un élément huméral (3) fixé dans la diaphyse humérale, est remarquable en ce que le ce...

Ce matériel (1) comprend une pièce rigide (2), notamment métallique, au moins partiellement revêtue d'une couche (3) d'un matériau bio-réactif, notamment à base d'hydroxyapatite de calcium ou de phosphate tricalcique. La surface externe (3a) de cette couche (3) est lissée, de telle sorte qu'elle ne présente pas d'aspérité (3b) s'étendant au-delà d'une surface d'enveloppe (S). Cette surface exte...

A method for the fabrication of mural cladding plates in light concrete comprises:- a) a mortar is cast into the bottom of a mould to produce the layer with the visible face of the plate, this mortar being made up of 15 to 40 % by volume of hydraulic binder, 40 to 75 % by volume of sand, 0.1 to 1 % by volume of fibres, 5 to 10 % by volume of meta kaolin, an anti-shrinking additive, a plasticizing ...

An expandable interbody fusion device in one embodiment includes a cylindrical body (10) defining a hollow interior (17) for receiving bone graft or bone substitute material. The body (10) is divided into a number of branches (24, 26, 40 and 41) connected to one another at a fixed end (20) and separated at an expandable end (18). The expandable cage may be inserted in its substantially cylindrical...

The cardboard container has a base (1a) with raised side sections (11,12) formed by folding the cardboard. The compact discs are stacked in the base area with an inserted stacking element (22) between them. The stacking element has a central slot and cut off sides thus protecting delicate areas of the compact disc. The cardboard sides are folded over the top and the rest of the cardboard base are ...

The invention concerns a method for treating a material based on concrete, mortar, cement, stone, stucco or the like, comprising steps which consist in: mixing one or several active products with a gel; applying a continuous coat of the resulting mixture over the entire surface of the material to be treated.

An automatic automotive cable braiding or pairing machine that does not require special foundation or anchoring for its mounting where in the design of its arrangements consisting of: clamp operated by a pneumatic or hydraulic actuator; a pneumatic-type pressing device or fastener that permits the torsion of cables in cut segments with constant pitches and operates with different gauges; and a tai...

The electronic device has a lock (12) which is actuated by a key (18) when its identification code matches that of the key. The lock has a cartridge (14) and a part (14A) in which at least one hole (16) for a key (18) is designed. The cartridge includes at least one facility for electrical connection (39), electronic facility with control memory for the storage of at least one identification code ...

The invention relates to inhibitors of the cellular growth and to their adjunctive to acid salts which are peptides with the formula A - B - D - E - F - (G)r - (K)s - L (I) where A, B, D, E, F, G. and K are -aminoacid residues and s and r are, individually, 0 or 1. L is univalent radical, such as aminogroup, N-substituted aminogroup, beta-hydroxyaminogroup, beta-hydroxyaminogroup, hydr...

Se refiere a nuevas eritromicinas y azalidas útiles como agentes antibacterianas y antiprotozoos y en aplicaciones en mamíferos, incluyendo el ser humano, así como en peces y aves. También refiere a composiciones farmacéuticas conteniendo los nuevos compuestos y procedimientos para el tratamiento de las infecciones bacterianas y provocadas por protozoos en mamíferos, peces y aves, mediante adminis...

Derivados de la eritromicina de fórmula general (2) representada en la figura 1, o una sal farmacéuticamente aceptable del mismo en la que: R es un grupo alquilo C3-8 ramificado en alfa, alquenilo C3-8, alquinilo C3-8, cicloalquilo C3-8, o cicloalquenil C5-8; X es - (CR5R6)g, en donde g es 0 o 1; R3 es - (CR5R6)mZ, en donde m es un número entero entre 0 y 6; R4 es hidrógeno; R5 y R6 se seleccionan...

Se describen nuevas formas cristalinas de un compuesto de Fórmula 1: También se describen composiciones farmacéuticas que comprenden estas formas y procedimientos para su preparación y uso.; Novel crystalline forms of a compound of Formula 1 are disclosed:Also disclosed are pharmaceutical compositions comprising these forms, and methods of their preparation and use.

Compuestos de fórmula 1 y a sales, promedicamentos y solvatos de éstos farmaceúticamente aceptables, en los que R1 y R2 son OR8, R2 es omesilo, otosilo, etc tambien R1 y R2 tomados juntos son figura A, R3 es OR10, R4 es H, C(O)alquilo(C1-18), C(O)Ar, etc, R5 es H, un alquilo C1-10, un alquinilo C3-10, etc, R17 es alquilo C1-20, etc, Rf es H, un -C(O9-imidazolilo, etc, A es H o halógeno, X es-C(O)-...

El invento brinda agentes y métodos mejorados para el tratamiento de enfermedades asociadas con depósitos amiloides de A Beta en el cerebro de un paciente. Dichos métodos implican la administración de agentes que inducen una respuesta inmune beneficiosa contra los depósitos amiloides. Los métodos son útiles para el tratamiento profiláctico y terapéutico del mal de Alzheimer. Los agentes preferidos...

The invention relates to erythromycin A derivatives having the general formula (I) : A-(CH2)n-N-(CH2)m-N-(CH2)r-O-N=M, where A is a phenyl group or a 5-6 membered heterocycle group, containing one or more heteroatoms selected from nitrogen, oxygen and sulphur, optionally substituted by the same or different 1 ... 3 groups, selected from alkyl or alkoxy C1-C4, linear or branched, alkylendioxy group...

The present invention provides nucleic acid molecules containing nucleotide sequences encoding helminth aminopeptidase enzymes, and antigenic fragments and functionally-equivalent variants thereof, their use in the preparation of vaccines for use against helminth parasites, and synthetic polypeptides encoded by them.

D-psicofuranose and D-psicopyranose derivatives represented by general formulae (I) and (II), useful as the key intermediates in a novel process for producing hydantocidin; wherein R<1> through R<8> may be the same or different from one another and each represents hydrogen or a hydroxyl-protecting group; and X represents optionally protected hydroxymethyl, carboxyl, carbamoyl or allophanoyl.

The invention provides passivated organic polymer supports, processes for their preparation and processes for their use in oligonucleotide synthesis that allow for highly efficient solid phase synthesis of oligonucleotides.

Methods and compounds, including compositions therefrom, are provided for determining the sequence of nucleic acid molecules. The methods permit the determination of multiple nucleic acid sequences simultaneously. The compounds are used as tags to generate tagged nucleic acid fragments which are complementary to a selected target nucleic acid molecule. Each tag is correlative with a particular nuc...

A three component electrical outlet box suitable for surface mounting is provided with a base having both locating legs and relatively rigid upstanding posts that are adapted to receive one of a plurality of covers, each cover having inwardly projecting lugs in its flexible side walls to be received in openings defined for this purpose in the posts. An electrical device such as a duplex plug with ...