The invention relates to a process for the preparation of racemic citalopram free base or an acid addition salt thereof and/or R- or S-citalopram as the free base or an acid addition salt thereof by separation of a mixture of R- and S-citalopram with more than 50% of one of the enantiomers into a fraction consisting of racemic citalopram and/or a fraction of S-citalopram or R-citalopram characteri...

The invention relates to a packaging device for a liquid that is to be dispensed drop by drop, comprising a container (1) with manually elastically deformable walls, which ends in a rigid neck (3) in which a head (4) for dispensing the liquid is mounted. A membrane (31) which is both hydrophilic and hydrophobic, advantageously antibacterial, is arranged in the dispensing head (4) across the passag...

Refractory metal products (12), such as tantalum on non-refractory conductive metal backings (14), e.g. copper, can be rejuvenated after metal consumption in selected zone by powder filling (28) the zones (18) and high energy heating (30) at high scan speed to sinter the added powder, without complete melting of the powder fill, thus establishing a microstructure consistent with the balance of the...

The invention relates to a process for the preparation of racemic citalopram free base or an acid addition salt thereof and/or R- or S-citalopram as the free base of an acid addition salt thereof by separation of a mixture of R- and S-citalopram with more than 50% of one of the enantiomers into a fraction consisting of racemic citalopram and/or a fraction of S-citalopram or R-citalopram characteri...

A method for producing concrete or mortar based on an exclusively vegetal aggregate, a mineral binding agent, and mixing water is described. Instead of the vegetal aggregate being premineralized in a separate step of the operation, 4 to 14 kg of a non-hydratizable, finely ground mineralizator is added for each cubic meter of vegetable aggregate when the concrete or mortar is being mixed. Raw calci...

The method and process for producing youthful appearing, small-pored, and smooth skin comprises pretreating the skin topically with retinoic acid, applying a contaminate in oil to the skin, and removing the contaminate by exploding or rupturing it with laser light. When treating the face, removing the contaminate requires only about 4 minutes. The laser light itself does not injure the skin but th...

The method for mobile payments includes successive operations, wherein the client (1) sends a word message (SMS) (4) on a mobile telephone to the service bank (2) of client (1), containing the code of client (1), including data for the individualization of the client (1) in the bank (2), the telephone number of the recipient (3) and the sum to be remitted. Bank (2) checks whether the code correspo...

The method includes local pretreating of the skin with retinoic acid. Contaminate in oil is applied on the skin and it is removed by rupturing with laser light. The contaminate removal requires only about 4 min. The laser light itself does not injure the skin but the rupture of the contaminate produces thermal injury in the high dermis leaving the epidermis intact. Repeated intermittent laser trea...

A liquid pharmaceutical composition of a GABA analog comprising at least one polyhydric alcohol containing 2 to 6 carbon atoms having a pH of about 5.50 to about 7.0 and additionally a two-component liquid pharmaceutical composition comprising a first component comprising a powder mixture comprising a GABA analog and a solid polyhydric alcohol, and a second component comprising a liquid base are d...

A device for examination of diabetic feet according to the invention enables the setting of a precise diagnosis on potential impairment of peripheral neural system on critical places of diabetics' feet by means of pictures of feet on a display. By this method, the white collar phenomenon is excluded, because the communication diagnostician - patient is taking place over the display with a touch la...

By the method a body-container of plastic packaging is made by a primary blank-press mould of polyethylene terephthalate (PET), which is placed in a die of exactly specified form of an expansion machine. As a result of treatment with hot air a secondary blank is produced having finally formed cylindrical body, bottom and closing surface. The secondary blank is further treated in the zone of the cl...

There is disclosed a water-reducible, chrome-free coating composition for providing corrosion protection to a substrate, such as a metal substrate. The deposited coating film is corrosion-resistant and, for coated articles which are threaded, e.g., steel fasteners, the coating provides a non-thread-filling coating. The coating composition contains particulate metal, such as particulate zinc or alu...

An alkali-free accelerator for sprayed concrete is prepared by dissolving aluminium sulphate and amorphous aluminium hydroxide in water which optionally contains one amine, and optionally adding at least one stabiliser, selected from hydroxycarboxylic acid and phosphoric acids and non-alkaline salts thereof, and at least one defoaming agent.

The present invention relates to novel peptides which are useful as antagonists of the beta₂ integrins, to pharmaceutical compositions comprising these peptides, to the use of the novel peptides for the manufacture of pharmaceutical compositions for the treatment of inflammatory diseases and human leukemias and for inhibiting leukocyte cell adhesion and migration in general, to a method...

In a computer system that employs virtual memory, multiple versions of a giv en page are stored: a directory version, a table version, and a data version. The data version contains the data that a software object believes to be stored in the page. The directory and table versions of the page contains versions of the page's contents that have been modified in some manner to comply with a restrictio...

The invention provides improved agents and methods for treatment of diseases associated with amyloid deposits of A² in the brain of a patient. Such methods entail administering agents that induce a beneficial immunogenic response against the amyloid deposit. The methods are useful for prophylactic and therapeutic treatment of Alzheimer's disease. Preferred agents including N-terminal fragments of ...

The present invention relates to processes for converting clarithromycin Form I to clarithromycin Form II, which include slurrying clarithromycin the Form I in water. The present invention also relates to processes for the preparation of clarithromycin Form II by converting erythromycin A to clarithromycin and thereafter converting clarithromycin Form I to clarithromycin Form II by slurrying.

The invention relates to perfluoroalkyl-containing complexes comprising sugar residues of the general formula (I), wherein R represents a mono- or oligosaccharide residue bound in the 1-OH or 1-SH position, Rf represents a perfluorated carbon chain, K is a metal complex and Y and Z are linker groups. The inventive complexes are suitable for use in intravenous lymphography, in tumor diagnosis and f...

Azithromycin in the form of a monohydrate comprising from 4.0% to 6.5% of water, a process for its preparation and its use in pharmaceutical compositions.

6-O-Carbamoyl ketolide antibacterials of the formula:wherein R1, R2, R3, R4, R5, R6, X, X', Y, and Y' are as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.