A navigation system for navigating an autonomous vehicle along a path that is confined by walls that are within range of on-board sensors is described. The system determines the relative location and orientation of the walls with respect to the vehicle. The system controls the steering angle and the ground speed of the vehicle by employing: (a) range data to establish free space in front of vehicl...

The building heat-insulating material on base of watery alkalized silic feed, obtained by comminution of solid and mixing of all feed ingredients, steaming of the feed mixture and thermal expansion of the dispersed semi-finished products, obtained from the steamed feed mixture, is provided for the utilization in the capacity of filling warmth-keeping laggings and aggregates for light-weight concre...

The invention concerns the field of organic chemistry, and more precisely, that of therapeutic chemistry. More particularly, the invention concerns novel esters derived from nucleosides of general formula (I) wherein: A represents a divalent group selected among -(CH2)n-, -(CH2)n -NH-, -(CH2)n -O-; (a); (b); (c); (d); (e); n is an integer ranging between 1 and 12; Z represents an amino, hydroxyl o...

The invention relates to the equipment for glass release from the bed frame or construction, wherein the glass is fixed. In particular, the invention relates to a process and a device for releasing the window glasses and windscreens (e. g., of motor-cars), fixed into the frame by means of a binding material, placed between the glass and the frame. The windscreens of the vehicles, fixed into the be...

SE REFIERE A UN METODO PARA TRATAR LO SINTOMAS DE ENFERMEDADES ADICTIVAS QUE COMPRENDE ADMINISTRAR UN AGENTE ACTIVO SELECCIONADO DE: a) UNA AMINA HETEROCICLICA DE FORMULA I DONDE R1, R2 Y R3 SON H, ALQUILO C3-C6, ALQUENILO C3-C5, ALQUINILO C3-C6, CICLOALQUILO C3-C7 O R1 Y R2 JUNTOS FORMAN UNA AMINA CICLICA C3-C7 CON HETEROATOMOS ADICIONALES; N ES 0-1; X ES H, ALQUILO C1-C6, HALOGENO, HIDROXI, ALCO...

SE REFIERE A COMPUESTOS BICICLO PIRAZOLES DE FORMULA I DONDE R Y R1 SON H, R', COR', COOR', SO2R', ENTRE OTROS; R' Y R" SON H, ARILO, ALQUILO C1-C6, CICLOALQUILO C3-C6, ENTRE OTROS; Ra, Rb, Rc, Rd SON H, CH2OR', ARILO; Ra Y Rb O Rc Y Rd JUNTO A C FORMAN UN CICLOALQUILO C3-C6 OPCIONALMENTE SUSTITUIDO; m y n SON 0-2; m+n ES MENOR DE 2. SON COMPUESTOS PREFERIDOS N-{5-FENILACETIL-4,6-DIHIDROPIRROLO[3,...

SE REFIERE A UN SISTEMA PARA LA PRODUCCION CONTINUA GOMAS DE MASCAR CON RELLENO LIQUIDO, QUE COMPRENDE: i) UN EXTRUSOR Y UN MECANISMO PARA RELLENAR EL CENTRO QUE PRODUCE CONTINUAMENTE UN CORDON DE MATERIAL DE GOMA DE MASCAR RELLENO EN EL CENTRO; ii) UN MECANISMO PARA LA FORMACION DE TABLETAS, QUE TIENE UNA PRIMERA CADENA GIRATORIA CON UNA PLURALIDAD DE ACANALADURAS MATRICES Y UN SEGUNDO MECANISMO ...

SE REFIERE A UNA FORMULACION OFTALMICA DE APLICACION TOPICA QUE COMPRENDE: a) UNA DROGA SELECTIVA PARA LA INHIBICION DE COX-2 DE BAJA SOLUBILIDAD EN AGUA SELECCIONADA DE UN COMPUESTO DE FORMULA I DONDE R3 ES IMIDA, AMINO, METILO; R4 ES H, ALCOXI, ALQUILO C1-C4; X ES N, CR5 DONDE R5 ES H, HALO; Z E Y SON C, N, QUE DEFINEN ATOMOS ADYACENTES DE UN ANILLO DE 5-6 MIEMBROS COMO CICLOPENTENONA, FURANONA,...

This invention described an ICE inhibitor prodrug (I) having good bioavailability. Compound of formula (I) is useful for treating IL-1 mediated diseases such as rheumatoid arthritis, inflammatory bowel disease, Crohn's disease, ulcerative colitis, inflammatory peritonitis, septic shock, pancreatitis, traumatic brain injury, organ transplant rejection, osteoarthritis, asthma, psoriasis, Alzheimer's...

The present invention relates to an oral vaccine comprising recombinant lactic acid bacteria expressing heterologous antigen in vivo intracellularly and/or the surface of the lactic acid bacterium as specific immunogenicity eliciting component for eliciting immunogenicity against the heterologous antigen, characterised in that the recombinant lactic acid bacterium is a Lactobacillus plantarum. Pr...

Machine has integrated vapor distribution circuit (3) with vapor input (12) connected to vapor feed and vapor output circuit (10). Vapor from output (10) is brought into contact with cover (4) of coffee liquid container (5), by system including hollow part (14) fitted with radial opening (15) and displaceable part (13). Displaceable part moves against action of spring inside part (14) via finger (...

2-amino-1,3-thiazole derivatives represented by formula (I) or (II): where R, R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof are useful as, for example, the treatment of cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases or neurodegenerative diseases.

The present invention relates to Card Payment Systems for use in a multi-currency environment. In particular, the present invention provides a system and method for identifying an appropriate currency for individual transactions conducted using a card payment system, using the steps of identifying (50) an identifier code (60(1-n)) from a payment card, and determining (52) from the identifier code ...

The present invention relates to pharmaceutical compositions and more particularly to a pharmaceutical composition containing (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-(3R, 5S)-3,5-dihydroxyhept-6-enoic acid or a pharmaceutically-acceptable salt thereof as the active ingredient, the composition having a coating containing a ferric oxide.

The invention provides an attenuated rotavirus population comprising a single variant or substantially a single variant which is defined by a nucleotide sequence encoding at least one of the major viral proteins designated as VP4 and VP7. The invention particularly provides a rotavirus population designated as P43. The invention further provides a novel formulation for a rotavirus vaccine which is...