NOVEL COMPOUNDS OF FORMULA ARE DISCLOSED. ALSO DISCLOSED IS A METHOD OF INHIBITING FARNESYL PROTEIN TRANSFERASE FUNCTION AND THEREFORE INHIBITING THE ABNORMAL GROWTH OF CELLS. THE METHOD COMPRISES ADMINISTERING A COMPOUND OF THE ABOVE FORMULA TO A BIOLOGICAL SYSTEM. IN PARTICULAR, THE METHOD INHIBITS THE ABNORMAL GROWTH OF CELLS IN A MAMMAL SUCH AS A HUMAN BEING.

A NOVEL CRYSTALLINE FORM (FORM L) OF THE ALDOSTERONE RECEPTOR ANTAGONIST DRUG EPLERENONE IS PROVIDED HAVING RELATIVELY HIGH PHYSICAL STABILITY AT NORMAL TEMPERATURES OF STORAGE AND USE. PHARMACEUTICAL COMPOSITIONS ARE ALSO PROVIDED COMPRISING FORM L EPLERENONE, OPTIONALLY ACCOMPANIED BY ONE OR MORE OTHER SOLID STATE FORMS OF EPLERENONE, IN A TOTAL UNIT DOSAGE AMOUNT OF EPLERENONE OF ABOUT 10 TO AB...

THE PRESENT INVENTION PROVIDES A CATALYST SYSTEM CAPABLE OF CATALYZING THE CARBONYLATION OF AN ETHYNICALLY UNSATURATED COMPOUND, WHICH SYSTEM IS OBTAINABLE BY COMBINING: a) A METAL OF GROUP VIB OR GROUP VIIIB OR A COMPOUND THEREOF, b) A BIDENTATE PHOSPHINE, ARSINE OR STIBINE LIGAND, AND c) AN ACID, WHEREIN SAID LIGAND IS PRESENT IN AT LEAST A 2:1 MOLAR EXCESS COMPARED TO SAID METAL OR SAID METAL I...

THE PRESENT INVENTION CONCERNS MORPHOLINYL CONTAINING BENZIMIDAZOLES HAVING INHIBITORY ACTIVITY ON THE REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS AND HAVING THE FORMULA A PRODRUG, N-OXIDE, ADDITION SALT, QUATERNARY AMINE, METAL COMPLEX OR STEREOCHEMICALLY ISOMERIC FORM THEREOF WHEREIN G IS A DIRECT BOND OR OPTIONALLY SUBSTITUTED C1-10ALKANEDIYL; R1 IS AR1 OR A MONOCYCLIC OR BICYCLIC HETEROCYCL...

THE INVENTION PROVIDES NOVEL BENZOIMIDAZOLONE-CARBOXAMIDE-DERIVED CARBAMATE 5-HT4 RECEPTOR AGONIST COMPOUNDS OF FORMULA (I): WHEREIN R1, R2, R3, R4, A AND B ARE DEFINED IN THE DISCLOSURE. THE INVENTION ALSO PROVIDES PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS, METHODS OF USING SUCH COMPOUNDS TO TREAT DISEASES ASSOCIATED WITH 5-HT4 RECEPTOR ACTIVITY, AND PROCESSES AND INTERMEDIATES USEFUL...

A METHOD AND SYSTEM FOR OFFLOADING I/O PROCESSING FROM A FIRST COMPUTER (101) TO A SECOND COMPUTER (121), USING RDMA-CAPABLE NETWORK INTERCONNECTS (111, 135), ARE DISCLOSED. THE METHOD AND SYSTEM INCLUDE A CLIENT (103) ON THE FIRST COMPUTER (101) COMMUNICATING OVER AN RDMA CONNECTION (117) TO A SERVER (123) ON THE SECOND COMPUTER (121) BY WAY OF A LIGHTWEIGHT INPUT/OUTPUT (LWIO) PROTOCOL. THE PROT...

THE PRESENT INVENTION IS CONCERNED WITH COMPOUNDS OF FORMULA (I) H WHEREIN R1 IS ARYL OR HETEROARYL; R2 IS HYDROGEN, LOWER-ALKYL, OR FLUORO-LOWER-ALKYL; R3 AND R4 INDEPENDENTLY FROM EACH OTHER ARE HYDROGEN, HYDROXYL, HALOGEN, LOWER-ALKYL, FLUOROLOWER-ALKYL, HYDROXYL-LOWER-ALKYL, LOWER-ALKOXY-LOWER-ALKYL, LOWER-ALKOXY, FLUOROLOWER-ALKOXY, HYDROXYL-LOWER-ALKOXY, LOWER-ALKOXY-LOWER-ALKOXY, OR LOWER-A...

METHODS OF PRODUCING CARBON BLACK IN A MULTI-STAGE REACTION ARE DESCRIBED. ALSO DESCRIBED IS CARBON BLACK FORMED THE PROCESSES.

COMPOUNDS OF FORMULA (1) WHEREIN R₁ IS 2-INDANYL, R₂ IS 1-METHYLPROPYL, R₃ IS A GROUP SELECTED FROM 2, 6- DIMETHYL-3-PYRIDYL OR 4,6-DIMETHYL-3-PYRIDYL, R₄ REPRESENTS METHYL AND R₅ REPRESENTS HYDROGEN OR METHYL OR, R₄ AND R₅ TOGETHER WITH THE NITROGEN ATOM TO WHICH THEY ARE ATTACHED REPRESENT MORPHOLINO AND PHARMACEUTICALLY ACCEPTABLE DERIVATIVES THEREOF ARE DESCRIBED, AS ARE PROCESSES FOR THEIR PR...

[PROBLEMS TO BE SOLVED] TO PROVIDE A CURABLE ORGANOPOLYSILOXANE COMPOSITION, WHEREIN THE COMPOSITION CAN BE LAMINATED DIRECTLY ON THE SURFACE OF AN EPOXY RESIN ANTICORROSIVE COATING FILM AND CAN FORM AN ANTIFOULING COATING FILM WHICH HAS IMPROVED ANTIFOULING PERFORMANCE COMPARED TO THE CONVENTIONAL ART. [MEANS FOR SOLVING THE PROBLEMS] A TWO-LIQUID TYPE OR THREE-LIQUID TYPE CURABLE ORGANOPOLYSILOX...

SUBSTITUTED AND PYRIDINES AND PYRIDAZINES HAVING ANGIOGENESIS INHIBITING ACTIVITY AND THE GENERALIZED STRUCTURAL FORMULA WHEREIN THE RING CONTAINING A, B, C, D, E, AND L IS PHENYL OR A NITROGEN-CONTAINING HETEROCYCLE; GROUPS X AND Y MAY BE ANY OF A VARIETY OF DEFINED LINKING UNITS; R1 AND R2 MAY BE DEFINED INDEPENDENT SUBSTITUENTS OR TOGETHER MAY BE A RING-DEFINDING BRIDGE; RING J MAY BE AN ARYL, ...

THE INVENTION RELATES TO COMPOUNDS OF FORMULA PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MUSCARINIC ANTAGONISTS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM.

ANTIBODIES THAT INTERACT WITH OSTEOPROTEGERIN LIGAND (OPGL) ARE DESCRIBED. METHOD OF TREATING OSTEOPENIC DISORDERS BY ADMINISTERING A PHARMACEUTICALLY EFFECTIVE AMOUNT OF ANTIBODIES TO OPGL ARE DESCRIBED. METHODS OF DETECTING THE AMOUNT OF OPGL IN A SAMPLE USING ANTIBODIES TO OPGL ARE DESCRIBED.

DISCLOSED ARE COMPOUNDS AND PHARMACEUTICALLY ACCEPTABLE SALTS OF FORMULA I WHEREIN R1, R2, R3, R4, R5, R6, R7, N, Q1, Q2, Q3, Y, AND X1- X4 ARE AS DEFINED HEREIN. COMPOUNDS OF FORMULA I ARE USEFUL IN THE TREATMENT OF DISEASES AND/OR CONDITIONS RELATED TO CELL PROLIFERATION, SUCH AS CANCER, INFLAMMATION, ARTHRITIS, ANGIOGENESIS, OR THE LIKE. ALSO DISCLOSED ARE PHARMACEUTICAL COMPOSITIONS COMPRISING...

THE PRESENT INVENTION RELATES TO CERTAIN NOVEL COMPOUNDS OF THE FORMULA I TO PROCESSES FOR PREPARING SUCH COMPOUNDS, TO THEIR THE UTILITY IN MODULATION OF NUCLEAR HORMONE RECEPTORS LIVER X RECEPTOR (LXR) Α (NR1H3) AND/OR Β (NR1H2) AND IN TREATING AND/OR PREVENTING CLINICAL CONDITIONS INCLUDING CARDIOVASCULAR DISEASES SUCH AS ATHEROSCLEROSIS; INFLAMMATORY DISEASES, ALZHEIMER’S DISEASE, LIPID DISORD...

25 METHOD AND APPARATUS FOR CONTINUOUS CASTING ABSTRACT 5 THE INVENTION IELALES TO A METHOD FOR THE CONTINUOUS CASTING- OF SLAB, THIN SLAB, BLOOM. PIELIMINWY SECTION, ROUND SECTION, TUBULAR SECTION OR BILLET STRANDS (1) AND THE LIKE FROM LIQUID METAL IN A CONTINUOUS CASTING PLANT (2) IN WHICH METAL DISCHAILGES PKN-PENDICULAILY DOWNWARDS FROM A MOULD (3). WHEIEIN THE METAL STRIP (1) IS THEN GUIDED ...

A SMALL SLENDER CONTAINER AND AN APPLICATOR THAT MAY BE USED TO STORE SMALL QUANTITY OF SUBSTANCE, SUCH AS CREAMS, LOTIONS, AND MAKE-UPS IN A SEALED ENVIRONMENT AND EASILY AND SANITARILY DISPENSES ITS CONTENT FOR APPLICATION AS DESIRED IS DISCLOSED. THE CONTENT OF THE SLENDER CONTAINER MAY BE PERMANENTLY SEALED WITH AN OPENING MEANS OR MAY BE SEALED WITH A HIGH VISCOSITY SUBSTANCE SUCH AS SILICONE...

METHOD FOR USE IN ANALYSING DEGRADATION ZINC OXIDE SURGE ARRESTER THE PRESENT INVENTION DISCLOSES A METHOD FOR USE IN ANALYZING ANY FORM OF DEGRADATION WITH RESPECT TO A SURGE ARRESTER. THE MAIN STEPS IN ACCORDANCE WITH A PREFERRED EMBODIMENT OF THE PRESENT INVENTION INCLUDE MEASURING THE TOTAL LEAKAGE CURRENT; DELAYING THE TOTAL LEAKAGE CURRENT AND EXTRACTING THE CAPACITIVE CURRENT FROM THAT OF T...

IR-ABSORBING TNTAGLIO INK PASTY INK FOR THE ENGRAVED STEEL DIE PRINTING PROCESS, HAVING A VISCOSITY VALUE ABOVE 3 PA.S, PREFERABLY ABOVE 5 PA.S AT 40'C, AND COMPRISING AN INFRARED ABSORBING MATERIAL, 5 WHEREIN SAID INFRARED ABSORBING MATERIAL IS A TRANSITION ELEMENT COMPOUND WHOSE IR- ABSORPTION IS A CONSEQUENCE OF ELECTRONIC TRANSITIONS WITHIN THE D-SHELL OF TRANSITION ELEMENT ATOMS OR IONS.

ELECTRICAL PARTT NONAQUEOUS-ELECTRALYTE CELL9 AND LEAD CONDUCTOR WITH INSULATING COATING LAYER AND SEALED VESSEL EACH FOR USE IN THESE 5 AN ELECTRICAL PART COMPRISING A LEAD CONDUCTOR AND A SEALED VESSEL INCLUDING A METAL LAYER, THE LEAD CONDUCTOR EXTENDING FROM THE INSIDE OF THE SEALED VESSEL TO THE OUTSIDE, WHEREIN THE LEAD CONDUCTOR AND THE SEALED VESSEL ARE FUSION-BONDED THROUGH A THERMAL ADHE...